A Case of Multiple Desmoplastic Trichoepithelioma

Moon, Seong Hun; Choi, Hyun Seok; Kwon, Hyoung Il; Ko, Joo Yeon; Kim, Jeong Eun

doi:10.5021/ad.2016.28.3.411

Cited by 5 publications

(3 citation statements)

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“…Histologically, DTE is characterized by thin cords of small basaloid cells in a densely sclerotic stroma (Figure 3, D). [49][50][51] Morphologically, DTE mimics morpheaform BCC (mBCC), which can be challenging to differentiate, especially in superficial biopsies. Histologic features that favor DTE are architectural symmetry, horn cysts with calcifications, narrow cellular aggregates, giant cell reactions, and follicular/sebaceous/infundibular differentiation (Table).…”

Section: Benign Hair-germ Tumors (Trichoepithelioma Andmentioning

confidence: 99%

Histologic Mimics of Basal Cell Carcinoma

Stanoszek

Wang

Harms

2017

Archives of Pathology &Amp; Laboratory Medicine

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Context.— Basal cell carcinoma (BCC) is the most common human malignant neoplasm and is a frequently encountered diagnosis in dermatopathology. Although BCC may be locally destructive, it rarely metastasizes. Many diagnostic entities display morphologic and immunophenotypic overlap with BCC, including nonneoplastic processes, such as follicular induction over dermatofibroma; benign follicular tumors, such as trichoblastoma, trichoepithelioma, or basaloid follicular hamartoma; and malignant tumors, such as sebaceous carcinoma or Merkel cell carcinoma. Thus, misdiagnosis has significant potential to result in overtreatment or undertreatment. Objective.— To review key features distinguishing BCC from histologic mimics, including current evidence regarding immunohistochemical markers useful for that distinction. Data Sources.— Review of pertinent literature on BCC immunohistochemistry and differential diagnosis. Conclusions.— In most cases, BCC can be reliably diagnosed by histopathologic features. Immunohistochemistry may provide useful ancillary data in certain cases. Awareness of potential mimics is critical to avoid misdiagnosis and resulting inappropriate management.

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Section: Benign Hair-germ Tumors (Trichoepithelioma Andmentioning

confidence: 99%

Histologic Mimics of Basal Cell Carcinoma

Stanoszek

Wang

Harms

2017

Archives of Pathology &Amp; Laboratory Medicine

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“…Surgical excision is the treatment of choice. At the same time, Mohs microscopic surgery is preferred for lesions, especially on the face [3]. Microscopically and clinically, it may be challenging to distinguish DTE from other cutaneous adnexal neoplasms.…”

Section: Introductionmentioning

confidence: 99%

“…Desmoplastic trichoepithelioma (DTE) is an uncommon benign appendageal skin cancer with an incidence of two per 10,000 and amounts to less than 1% of all cutaneous tumors [ 1 , 2 ]. It is a clear-cut version of trichoepithelioma because of its unique clinical and histopathological features [ 3 ]. It usually presents as a single lesion, although in some exceptional cases, patients with numerous lesions have also been reported [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%