A Case of Mullerian Cyst Arising in Posterior Mediastinum

Kobayashi, Satoru; Inoue, Takashi; Karube, Yoko; Hayama, Makio; Oyaizu, Takeshi; Honma, Koichi; Chida, Masayuki

doi:10.5761/atcs.cr.11.01678

Cited by 24 publications

(16 citation statements)

References 8 publications

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“…Recently, Hattori[2] described the first case of a ciliated cyst of probable Müllerian origin arising in the posterior mediastinum, a so-called Hattori’s cyst. Since that time, several additional cases have been reported[3,4]. We found a posterior mediastinal cyst with Müllerian differentiation that was consistent with previous description of Hattori’s cyst.…”

supporting

confidence: 91%

A Ciliated Cyst with Müllerian Differentiation Arising in the Posterior Mediastinum

et al. 2014

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supporting

confidence: 91%

A Ciliated Cyst with Müllerian Differentiation Arising in the Posterior Mediastinum

et al. 2014

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“…In addition, mediastinal Mullerian cysts also have ciliated columnar epithelium, but in our case, the cyst had gastrointestinal grands. Furthermore, all reported cases of mediastinal Mullerian cysts were occurred in female (7). Thus, we concluded that the cyst was to be an enteric cyst.…”

Section: Discussionmentioning

confidence: 73%

Adenocarcinoma arising from an enteric cyst of the posterior mediastinum

et al. 2018

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Mediastinal enteric cysts are rare congenital thoracic cysts. The majority of mediastinal enteric cysts occur in infants, while they are rare in adults. Although most of these cysts are benign, surgical resection is sometimes performed, and malignant changes found in enteric cysts are rare. A 52-year-old man was incidentally discovered to have a posterior mediastinal mass and we excised the mass thoracoscopically. Histopathological findings showed an enteric cyst with adenocarcinoma. Comparing the pathological and magnetic resonance imaging (MRI) findings, MRI would help to detect malignant changes in such cysts.Although malignant changes found in mediastinal enteric cysts are extremely rare, clinicians should always keep in mind that those cysts have malignant potential and careful evaluation of MRI would be a clue for surgical indication.

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“…Müllerian kistler, genellikle genitoüriner organların etrafında veya pelviste ve nadiren de kadın genital sistemden ayrı retroperitonda bulunur (6). Gelişimsel olarak müllerian kanalının kalıntılarından ortaya çıkar ve müllerian kanal regresyonunun yolu boyunca herhangi bir yerde bulunabilir.…”

Section: Discussionunclassified

“…Daha önce bu olguların 6'sına bronkojenik kist tanısı, 3'üne de benign seröz kist tanısı verildiği görülmüştür (9). Genel olarak perimenopozal dönem boyunca gelişen bu kistlerin, hormon replasman tedavisi, histerektomi ve ooferektomi gibi jinekolojik durumlarla ya da obezite ile ilişkili olduğu bildirilmiştir, ancak etiyolojisi halen belirsizdir (4,6). Bilinen patogenez teorileri; endometriozis, endosalpingiozis, endoservikozis ve adenomyozis gibi jinekolojik hastalıklardır.…”

Section: Discussionunclassified

Mediastinal cyst with mullerian differentiation: hattori cyst

Ünay¹,

Arslan²,

Erdoğan³

et al. 2019

JCurrPath

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ÖZET Amaç: Müllerian diferansiyasyon gösteren mediastinal kist, primer konjenital mediastinal kistler içinde nadir izlenen bir antitedir. Arka mediasten yerleşimlidir. İlk defa 2005 yılında Hattori tarafından tanımlanmış ve Hattori kisti olarak da isimlendirilmiştir. Tanı, histolojik olarak müllerian farklılaşma gösteren silyalı epitel varlığı ile konulur. Tipik olarak kist epiteli ER, PR, PAX8 ve WT-1 ile, kist duvarını oluşturan stroma α α-düz kas aktin (α αSMA) ile pozitiftir.Olgu: Olgumuz 42 yaşında, paravertebral yerleşimli, ER, PR ve WT-1 pozitif epitele sahip müllerian orijinli kistik lezyonla başvuran ve Hattori Kisti tanısı almış kadın hastadır.Sonuç: Olgu, diğer mediastinal kistlerin ayırıcı tanısında akılda tutulması gereken nadir bir antite olması nedeniyle sunulmuştur. ABSTRACTAim: Mediastinal cyst with mullerian differentiation is a rare entity among primary congenital mediastinal cysts. This cyst is located in the posterior mediastinum. It was first described by Hattori in 2005 and named as Hattori cyst. Histopathologically, diagnosis is based on the presence of ciliated epithelium with mullerian differentiation. Typically, the cyst epithelium is positive with ER, PR, PAX8 and WT-1, and the stroma constituting the cyst wall is positive with α α-smooth muscle actin (α α SMA).Case: Herein, we presented a 42-year-old female patient with paravertebral cystic lesion who was diagnosed as Hattori Cyst due to the mullerian origin of epithelium which was positive with ER, PR and WT-1. Conclusion:The case is presented because of being a rare entity that should be kept in mind in the differential diagnosis of other mediastinal cysts.Daha önce 27-30 Ekim 2018 tarihinde, Ankara'da yapılan 28. Ulusal Patoloji Kongresi'nde "poster sunumu" olarak sunulmuştur.

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A Case of Mullerian Cyst Arising in Posterior Mediastinum

Cited by 24 publications

References 8 publications

A Ciliated Cyst with Müllerian Differentiation Arising in the Posterior Mediastinum

A Ciliated Cyst with Müllerian Differentiation Arising in the Posterior Mediastinum

Adenocarcinoma arising from an enteric cyst of the posterior mediastinum

Mediastinal cyst with mullerian differentiation: hattori cyst

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