A case of metastatic liver cancer with hormone secretion: a case report

Abstract

Adrenocortical carcinoma (ACC) is a rare and challenging cancer with an incidence of 0.72 per million cases per year (1) and with a poor prognosis (2). ACC affects females more frequently than males (1.5:1) (3). The patients usually suffer from primary or metastatic tumors, and 40-60% of the tumors have hormone secretion function to cause Cushing's syndrome (CS) and hypercortisolism (4).Unfortunately, metastatic and recurrent of ACC exhibit poor 5-survival rates of less than 15% (2), the optimal management and clinical outcomes of ACC remain illdefined. Due to the failure of effective treatment, surgery remains the main treatment for ACC, which includes distant resectable metastases and ACC recurrent (2).