A Case of Long-Lasting Localized Pemphigus vulgaris of the Scalp

Lapière, Kim; Caers, Sarah; Lambert, Julien

doi:10.1159/000079607

Cited by 14 publications

(10 citation statements)

References 3 publications

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“…Different patterns of hair loss have been reported in PV, including anagen shedding,[5] as observed in our patient, scarring alopecia,[6] and tufted folliculitis. [7] Some authors suggest that the scarring would result from the combination of acantholysis and secondary bacterial infection.…”

Section: Discussionsupporting

confidence: 53%

Acantholytic hair casts: A dermoscopic sign of pemphigus vulgaris of the scalp

Pirmez

2012

Int J Trichol

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We report the dermoscopic features of pemphigus vulgaris (PV) involving the scalp of a 57-year-old African-American female. Among our findings, there were hair casts – movable tubular structures that envelop the hair shafts. We suggest that the development of those casts occurs through acantholysis within the outer root sheath, a mechanism not yet considered in the literature. This report also highlights how dermoscopy may contribute to the evaluation of disease activity, especially in those cases of PV in which scalp involvement is recalcitrant to treatment. Finally, we recommend that the presence of hair casts should herald the need of therapy adjustment for better disease control.

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Section: Discussionsupporting

confidence: 53%

Acantholytic hair casts: A dermoscopic sign of pemphigus vulgaris of the scalp

Pirmez

2012

Int J Trichol

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“…In a survey of the English literature, 26 reports of long standing localized PV and six cases confined to the scalp have been described previously (Table ). To our knowledge, PV involving the scalp may lead to erythemas, erosions, hair loss, and tufted folliculitis . Our patient presented with initial and persistent vegetating plaques on the scalp for more than 1 year without progression to any other location.…”

Section: Localized Pemphigus Vulgaris On the Scalpmentioning

confidence: 73%

Pemphigus vulgaris with vegetating feature confined to the scalp

Zhang

Xiao

et al. 2018

Int J Dermatology

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“…It is not infrequently involved at the very beginning of the disease 3 . PV localized to the scalp has even been reported as the sole manifestation of the disease for years 4 . On the other hand, pemphigus may become localized and recalcitrant on the scalp for months or even years despite clearing of lesions from other involved areas 5,6 .…”

Section: Discussionmentioning

confidence: 99%

“…3 PV localized to the scalp has even been reported as the sole manifestation of the disease for years. 4 On the other hand, pemphigus may become localized and recalcitrant on the scalp for months or even years despite clearing of lesions from other involved areas. 5,6 The scalp predilection is due to the great volume of PV antigens offered by follicular epithelium distributed in the ORS and matrix.…”

Section: Discussionmentioning

confidence: 99%