A case of intestinal T-cell lymphoma with repeated episodes of perforation

Yamamoto, Kyosuke; Shiraishi, T; Ajiki, Tetsuo; Imai, Yukihiro; Oyanagi, Harumasa; Saito, Yoichi

doi:10.1007/bf02781683

Cited by 18 publications

(9 citation statements)

References 19 publications

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“…Primary colorectal lymphoma accounts for only about 0.2% of large intestinal malignancies 2 ) . Most such lymphomas are B-cell origin, and T-cell lymphoma of the gastrointestinal tract is extremely rare 3 ) .…”

Section: Introductionmentioning

confidence: 99%

Primary T-cell Lymphoma of the Colon

Son

Rhee

Kim

et al. 1997

Korean J Intern Med

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A 40-year-old woman had been diagnosed with Crohns disease in September 1994, but later examinations revealed a primary T-cell lymphoma of the colon. Colonoscopic and histological examination showed ulcerative lesions simulating Crohns disease involving the entire colon and the terminal ileum, and she was first diagnosed as having Crohns disease. Differential therapeutic strategies, including corticosteroid, had improved the symptoms which were dominated by abdominal pain. When she visited our institute in April 1995, she presented with bloody stool twice a day, 7kg weight loss in a period of six months and a slightly painful abdomen. Colonoscopic finding showed geographic ulceration on the entire colon, especially rectum and terminal ileum. The histologic examination of specimens from colonoscopic biopsy showed primary peripheral T-cell lymphoma of the colon. Any dense lymphocyte infiltrates seen in the biopsy specimens obtained from lesions simulating ulcerative colitis or Crohns disease should be assessed to exclude intestinal lymphoma

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Section: Introductionmentioning

confidence: 99%

Primary T-cell Lymphoma of the Colon

Son

Rhee

Kim

et al. 1997

Korean J Intern Med

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“…Most primary gastrointestinal lymphomas have been of a B-cell origin. Only a few cases are reported to be positive for T-cell markers6, 14). The most common site of involvement for gastrointestinal T-cell lymphoma is the small bowel, and other sites are exceptionally rare.…”

Section: Discussionmentioning

confidence: 99%

Anorectal and gastric peripheral T-cell lymphoma, unspecified in a non-AIDS patient

Eum

Kim

et al. 2006

Korean J Intern Med

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Anorectum is a rare location for malignant lymphoma. Involvement of is rare even for the lymphoma associated with acquired immune deficiency syndrome (AIDS), and AIDS has a relatively increased frequency of anorectal lymphoma. Most lymphomas in AIDS patients are of a B-cell origin, and T-cell lymphoma of the gastrointestinal tract is extremely rare. We report here on a case of anorectal and gastric peripheral T-cell lymphoma, unspecified (PTCLu) in a non-AIDS patient. A previously healthy 29-year-old man presented with hematochezia and tenesmus that he had suffered with for the previous 2 months. Sigmoidoscopy showed anal and rectal submucosal tumor. Multiple round-shaped, flat and elevated lesions were noted on the gastric antrum and body as well. He underwent excisional biopsy for the anal mass and the diagnosis was PTCLu. Biopsies of the gastric lesions gave the same diagnosis. There was no lymphoma involved in the bone marrow. At admission, no antibodies against human immunodeficiency virus were detected. He underwent systemic chemotherapy and upfront autologous stem cell transplantation.

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“…d In cut surface of resection specimen, consistency of the tumor is homogenous and surface of the tumor is smooth (arrows). Ulceration or necrosis was not noted lymphoma that had extensive mucosal ulceration have been reported [15,17,18,19]. Recently, peripheral Tcell lymphoma manifested as segmental colonic ulceration has been reported (Fig.…”

Section: Circumferential Lesion With Extensive Ulcerationmentioning

confidence: 91%

“…The clinical evolution of PTCL of the colon is usually very aggressive. Perforation of the bowel is common and most of patients die within several years after presentation [15,16,17,18]. Several authors have proposed that angiocentric infiltration of atypical lymphocytes, a unique histologic feature of PTCL, might be associated with bowel ischemia and extensive tissue necrosis in gastrointestinal PTCL [19].…”

Section: Pathologic Conceptsmentioning

confidence: 98%

Primary colorectal lymphoma: spectrum of imaging findings with pathologic correlation

et al. 2002

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Primary colorectal lymphoma is a very uncommon disease; therefore, it has received little attention in the radiology literature. Moreover, imaging features of newly described pathologic subtypes have not been reported such as low-grade B-cell lymphoma arising from mucosa-associated lymphoid tissue and peripheral T-cell lymphoma that involves colorectal area. We retrospectively reviewed double-contrast barium enema and CT scans in the patients with primary colorectal lymphoma. In this article the radiologic appearances of primary colorectal lymphoma are categorized into focal lesion and diffuse lesion. Focal lesion includes polypoid mass, circumferential infiltration with smooth mucosal surface, circumferential infiltration with extensive ulceration, cavitary mass, mucosal nodularity, and mucosal fold thickening. Diffuse lesion includes diffuse ulcerative lesion and diffuse nodular lesion. Peripheral T-cell lymphomas that involve the colon manifested as either a diffuse or focal segmental lesion and showed extensive mucosal ulceration. These findings are similar to those of Crohn's disease or tuberculous colitis and are different from those of previously reported colorectal lymphoma. Low-grade B-cell lymphoma arising from mucosa-associated lymphoid tissue manifest as multiple mucosal nodularity. The imaging features of primary colorectal lymphoma are quite variable and overlap with other colonic pathology; however, it is important for radiologists to know the imaging features of primary colorectal lymphoma with their pathologic correlation.

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A case of intestinal T-cell lymphoma with repeated episodes of perforation

Cited by 18 publications

References 19 publications

Primary T-cell Lymphoma of the Colon

Primary T-cell Lymphoma of the Colon

Anorectal and gastric peripheral T-cell lymphoma, unspecified in a non-AIDS patient

Primary colorectal lymphoma: spectrum of imaging findings with pathologic correlation

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