A Case of Heterotopic Mesenteric Ossification after Multiple Pelvic Bone Fracture

泰寛, 林; 博之, 高村; 慶史, 中村; 秀人, 藤田; 致, 二宮; 元一, 西村; 隆, 藤村; 正都, 萱原; 哲生, 太田

doi:10.5833/jjgs.42.1621

Cited by 2 publications

(8 citation statements)

References 10 publications

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“…[4][5][6][7][8][9][10][11][12] Additional therapy to prevent HMO after the histological HMO diagnosis was performed in 4 cases. [6][7][8]13 In two cases, the patient was administrated NSAIDs; in others, cimetidine. 7,13 A preoperative diagnosis is often difficult.…”

Section: Discussionmentioning

confidence: 99%

“…[6][7][8]13 In two cases, the patient was administrated NSAIDs; in others, cimetidine. 7,13 A preoperative diagnosis is often difficult. In some cases, the ossifications were detected by the CT scan.…”

Section: Discussionmentioning

confidence: 99%

“…The symptoms of HMO are shown after a laparotomy or abdominal injury in 16 cases. 1,3,4,6,7,[9][10][11]13,[19][20][21][22] In 3 cases reported, heterotopic bone formation was observed along an abdominal midline incision, which was thought to have led to the HMO. 2,7,10 However, this hypothesis may be incorrect, as 7 cases reported had not experienced an operation or abdominal injury prior to developing HMO.…”

Section: Discussionmentioning

confidence: 99%

“…According to previous reports, NSAIDs, cimetidine, diphosphonates, and prophylactic radiation therapy have been recommended for the prevention of HMO recurrence in symptomatic patients. 7,11,13,16,18,23,27,28 We found only 4 reports describing the use of additional therapy. [6][7][8]13 Two authors followed up with conservative observation if no symptoms of recurrence were present.…”

Section: Discussionmentioning

confidence: 99%

“…7,11,13,16,18,23,27,28 We found only 4 reports describing the use of additional therapy. [6][7][8]13 Two authors followed up with conservative observation if no symptoms of recurrence were present. 6,8 Lai et al 7 used NSAIDs as an additional therapy after surgery, while Hayashi et al 13 used NSAIDs and cimetidine.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Heterotopic Mesenteric Ossification After a Ruptured Abdominal Aortic Aneurism: Case Report With a Review of Literatures

Honjo

Kumagai

Ishiguro

et al. 2014

International Surgery

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Heterotopic mesenteric ossification (HMO) is a rare disease that results in intra-abdominal ossification of unknown origin. An 88-year-old man developed an intestinal obstruction 2 weeks after undergoing an operation for a ruptured abdominal aortic aneurysm, resulting in intestinal obstructions those did not improved concervatively. During relaparotomy performed 30 days after the first operation, hard adhesions of the small intestine and mesentery were found; these adhesions were difficult to separate without damaging the serosa of the small intestine. We removed 240 cm of the small intestine and performed a jejuno-ileo anastomosis. Microscopically, trabecular bone tissue had increased irregularly in the fat tissue of the nodules with fibrosis, which were partially lined with osteoblasts. Accordingly, we histopathologically diagnosed the patient as having HMO. The patient was treated with NSAIDs and cimetidine to prevent the recurrence of HMO. No signs of recurrence have occurred as of one year after the second operation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Heterotopic Mesenteric Ossification After a Ruptured Abdominal Aortic Aneurism: Case Report With a Review of Literatures

Honjo

Kumagai

Ishiguro

et al. 2014

International Surgery

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A case report and literature review of heterotopic mesenteric ossification

Althaqafi

Assiri

Aloufi

et al. 2021

International Journal of Surgery Case Reports

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Introduction and importance Heterotopic mesenteric ossification is a benign bony tissue growth in the mesentery that mostly follows repetitive or severe abdominal injuries leading to reactive bone formation in the mesentery. There are only 73 cases (51 publications) identified in the literature up to the beginning of 2020. Case presentation 45-year-old Saudi male underwent multiple laparotomies to manage complicated appendicitis which ended with a diverting ileostomy and a colostomy as a mucus fistula. After 9 months, the patient was admitted to the General Surgery department in Al-Hada Armed Forces Hospital for an open ileostomy and colostomy reversal surgery where several irregular bone-like tissues of hard consistency and sharp edges with some spindle-shaped structures resembling needles were found in the mesentery of the small intestine and histopathology revealed of trabecular bone fragments confirming the diagnosis. Clinical discussion The majority of cases occur mid to late adulthood with a predilection in the male gender, and usually present with bowel obstruction or an enterocutaneous fistula. Although it has no malignant potential, it may cause severe bowel obstruction that can lead to mortality, it's a rare occurrence and, therefore, is difficult to diagnose among many common abdominal disturbances. Conclusion Here we report a rare case of heterotopic mesenteric ossification, which should be considered as one of the delayed complications of abdominal surgery or trauma. The time range of expecting the presentation of heterotopic mesenteric ossification following major abdominal trauma or surgery should be extended and continuously considered during differential diagnosis.

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A Case of Heterotopic Mesenteric Ossification after Multiple Pelvic Bone Fracture

Cited by 2 publications

References 10 publications

Heterotopic Mesenteric Ossification After a Ruptured Abdominal Aortic Aneurism: Case Report With a Review of Literatures

Heterotopic Mesenteric Ossification After a Ruptured Abdominal Aortic Aneurism: Case Report With a Review of Literatures

A case report and literature review of heterotopic mesenteric ossification

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