A case of herpes simplex 2 encephalitis with an unusual radiographic manifestation

Liu, Fang-Yu; Mouhayyar, Christopher El; Mamtani, Rishi; Dammann, Fabian; Basein, Tinzar

doi:10.1016/j.idcr.2020.e00884

Cited by 7 publications

(2 citation statements)

References 12 publications

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“…HSV-2 is not easy to diagnose like HSV-1 CNS infection based on temporal lobe involvement, therefore, it needs to perform lumbar puncture and HSV PCR on CSF uid. HSV-2 usually has atypical radiographic ndings (3,4). CNS complications of HSV-2 infection are more frequently found in immunocompromised patients, especially in HIV infection (5,6,7) Pelligra et al studied neonatal HSV-2 encephalitis.…”

Section: Discussionmentioning

confidence: 99%

HSV-2 induced Cerebellitis; A reactivatation of HSV-2 by SARS Covid -2 infection, A case Presentation

Ehsanipur

Vafaee-Shahi

Tahernia

et al. 2022

Preprint

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Background: Herpes simplex virus type-2 could hardly lead to encephalitis in human-being. Some DNA viruses could be reactivated by COVID-19 infection such as HSV-1 and HSV-2 viruses. An uncommon presentation of HSV-2 was detected as cerebellitis in this patient. It could be concluded that SARS COVID-2 can reactivate DNA viruses such as HSV-2. Case Presentation: Here we report a one-year-old girl infant with cerebellum involvement secondary to herpes simplex virus type 2 infection. Conclusion: The patient was treated for three weeks with intravenous acyclovir and oral prednisolone. Finally, during her neurological follow-ups in a 9 months period of time, she was able to walk with minimal ataxia.

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Section: Discussionmentioning

confidence: 99%

HSV-2 induced Cerebellitis; A reactivatation of HSV-2 by SARS Covid -2 infection, A case Presentation

Ehsanipur

Vafaee-Shahi

Tahernia

et al. 2022

Preprint

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“…Extrapyramidal symptoms are less common. While this is most frequently caused by HSV-1, it can rarely be due to HSV-2 invasion in up to 2-10% of HSV encephalitis cases (2,3).…”

Section: Introductionmentioning

confidence: 99%

Case Report: HSV-2 Encephalitis Presenting With Chorea; Effects of Infection Alone or Combination of Infection and Autoimmunity?

Колесник

Ballout²,

Hameed³

et al. 2021

Front. Neurol.

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Background: Chorea as a symptom of late-onset post-infectious autoimmune encephalitis has been reported with HSV-1 but not HSV-2 encephalitis. Extrapyramidal symptoms are typically associated with the presence of anti-NMDA receptor antibodies but may also exist in antibody-negative individuals.Case: This case highlights a patient who presented with mental status changes and chorea as the initial manifestation of HSV-2 encephalitis. The choreiform movements failed to respond to antiviral medications but were rapidly responsive to plasmapheresis, which, together with abnormal intrathecal immunoglobulin synthesis, suggests a potential contribution of parainfectious immune-mediated process. The patient made a full recovery and a complete resolution of the chorea.Discussion: This is the first case associating HSV-2 encephalitis presentation with chorea. The neurological complications, including chorea, are largely related to active CNS HSV-2 infection, possibly together with triggered CNS autoimmunity despite undetectable CSF neuronal autoantibodies and normal neuroimaging. Early diagnosis and treatment with antiviral agent and immune therapies might be pivotal to optimize the clinical outcome.

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Child with Acute Neurological Emergency

Mertiri,

Rossi,

Huisman

et al. 2024

IDKD Springer Series

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Children with acute neurological emergencies present to the ER with a wide spectrum of symptoms and signs. Neuroimaging plays an important role because of limitations such as gathering an accurate patient history and difficulties in performing a detailed neurological examination in the ER, particularly in young patients. The goal of this chapter is to discuss the neuroimaging findings of the most frequent causes of acute emergencies in children, as well as of some less frequently encountered entities.

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A case of herpes simplex 2 encephalitis with an unusual radiographic manifestation

Cited by 7 publications

References 12 publications

HSV-2 induced Cerebellitis; A reactivatation of HSV-2 by SARS Covid -2 infection, A case Presentation

HSV-2 induced Cerebellitis; A reactivatation of HSV-2 by SARS Covid -2 infection, A case Presentation

Case Report: HSV-2 Encephalitis Presenting With Chorea; Effects of Infection Alone or Combination of Infection and Autoimmunity?

Child with Acute Neurological Emergency

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