A Case of Hafnia Alvei and Candida Auris Bloodstream Infection in Patients With Covid-19

Emergence of Mobile Colistin Resistance Genes within Los Angeles County Wastewater

“…Given the gaps in our draft genome assembly, we cannot confirm if the mcr -9.1 identified in this study is encoded in the H. alvei chromosome or a part of an unassembled plasmid. Despite reports of increased H. alvei infections in immunocompromised patients during the COVID-19 pandemic, − there were no corresponding sequenced data in the NCBI database. For WS to reach its full potential, there is a need for more routine sequencing of clinical bacteria genomes particularly when ARGs (e.g., mcr ) can be harbored in intrinsically resistant bacterial hosts.…”

"Hafnia alvei Urinary Tract Infection in A Patient with Multimorbidity After Covid19 - A Case Report"

“…Except for a urinary infection in a healthy child [11], all the other cases regard immunocompromised patients, thus underlining the role of Hafnia alvei as an opportunistic pathogen. Until now, there are three known cases of patients who developed Hafnia alvei infections in the context of COVID-19, a bloodstream coinfection with Candida auris and two cases of ventilator-associated pneumonia [22,34,35]. We present a case of a successfully treated…”

“…In earlier studies, its connection to the clinical infection is debated [5] but after 2000, there is an increasing number of case reports in which Hafnia alvei is involved in human infections. For example, Hafnia alvei is reported to cause complicated [6][7][8][9] and uncomplicated UTIs [11], bacteremia and sepsis [12][13][14][15][16][17][18][19][20][21][22][23], hemolytic uremic syndrome [24], peritonitis [25,26], chorioamnionitis and preterm birth [27], deep infection in open fractures [28],…”