A case of gastric metastasis from renal cell cancer during the sequential targeted therapy

Uehara, Sho; Yuasa, Takeshi; Fujisaki, Junko; Fujii, Yasuhisa; Yamamoto, Shinya; Masuda, Hitoshi; Fukui, Iwao; Yonese, Junji

doi:10.1007/s13691-017-0286-x

Cited by 3 publications

(5 citation statements)

References 14 publications

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“…However, here, we present a case of metastases not only to the bladder but to the peritoneum and perigastric region (Figure 2). Metastases to the peritoneum are found in about 1-2% of cases, while for the gastric region, only 0.2-0.7% [24][25][26][27]. Metastases can be synchronous or metachronic.…”

Section: Discussionmentioning

confidence: 99%

Giant Abdominal Mass: Papillary Renal Cell Carcinoma with Metastases to the Bladder, Omentum and Perigastric Tissue

Kang¹,

Silva²,

Pereira³

et al. 2020

JSO

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Papillary renal cell carcinoma is an uncommon malignant tumor, which rarely metastases to the bladder and/or omentum. We report the case of a 71-year-old woman with macrohematuria for two years and a large mass on the right flank. Thus, we present a brief review of the literature regarding the classification, clinical manifestations, diagnosis, immunohistochemical profile, and treatment of this neoplasm. Special attention was given to the role of immunohistochemistry, which was decisive for the determination of multiple metastases, as well as the study by imaging exams, which defined the best surgical approach.

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Section: Discussionmentioning

confidence: 99%

Giant Abdominal Mass: Papillary Renal Cell Carcinoma with Metastases to the Bladder, Omentum and Perigastric Tissue

Kang¹,

Silva²,

Pereira³

et al. 2020

JSO

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“…Whereas two patients had no symptoms associated with the gastrointestinal system. 131,140 Esophagogastroduodenoscopy is often necessary for diagnosis and localized treatment. 131 The presence of gastric metastases is considered an important indicator of advanced disease.…”

Section: Malign Melanomamentioning

confidence: 99%

“…131,140 Esophagogastroduodenoscopy is often necessary for diagnosis and localized treatment. 131 The presence of gastric metastases is considered an important indicator of advanced disease. 149 Treatment options varied depending on the stage of the metastasis including endoscopic resection, partial or total gastrectomy, chemotherapy, and palliative care.…”

Section: Malign Melanomamentioning

confidence: 99%

Metastasis to the stomach: a systematic review

Ibrahimli,

Aliyev,

Majidli

et al. 2023

F1000Res

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Background: This study reviews the literature on gastric metastases (GM) in terms of diagnosis, treatment, and outcomes. The goal of this study was to provide clinicians with a reliable and beneficial source to understand gastric metastases arising from various primary tumors and to present the growing literature in an easily accessible form. Methods: Articles published in English language from implementation of MEDLINE and Cochrane databases until May 2022 were considered for the systematic review. Articles other than English language, letters to the editor, posters, and clinical images were excluded. Hematogenous and lymphogenic metastases were included whereas direct tumoral invasion and seeding were excluded. Articles and abstracts were analyzed and last selection was done after cross-referencing and by use of defined eligibility criteria. Results: In total 1,521 publications were identified and 170 articles were finally included totaling 186 patients with GM. The median age of patients was 62 years. Gynecologic cancer was the most common cancer type causing GM (67 patients), followed by lung cancer (33 patients), renal cancer (20 patients), and melanoma (19 patients). One of the main treatment methods performed for metastasis was resection surgery (n=62), sometimes combined with chemotherapy (ChT) or immunotherapy. ChT was the other most used treatment method (n=78). Also, immunotherapy was amongst the most preferred treatment options after surgery and ChT (n=10). Conclusions: As 172 case reports were screened in the systematic review from different journals, heterogeneity was inevitable. Some articles missed important information such as complete follow-up or clinical information. Moreover, since all of the included articles were case reports quality assessment could not be performed. Among 172 case reports reviewed, resection surgery was performed the most and was sometimes combined with ChT and immunotherapy. Further research about what type of treatment has the best outcomes for patients with gastric metastases is needed.

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“…Metastatic RCC is currently treated with various targeted agents and immune checkpoint inhibitors 1–3 . As their overall survival periods getting longer, we may encounter unusual visceral metastases more 1–4 . We present a valuable case of esophagus and bladder metastasis from RCC discovered in a routine CT scan during sequential targeted treatments.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3] As their overall survival periods getting longer, we may encounter unusual visceral metastases more. [1][2][3][4] We present a valuable case of esophagus and bladder metastasis from RCC discovered in a routine CT scan during sequential targeted treatments.…”

Section: Introductionmentioning

confidence: 99%

Unusual metastasis from renal cell cancer after partial nephrectomy and sequential targeted therapy

et al. 2021

Self Cite

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Introduction Metastatic renal cell carcinoma is treated with various regimens. As their outcomes are improving and follow‐up periods are growing longer, the rate of unusual visceral metastases may increase. Case presentation A 68‐year‐old man diagnosed with lung, pancreatic, and renal metastases 9 years after left partial nephrectomy and a diagnosis of pT1a clear cell renal cell carcinoma started molecular targeted therapy using sunitinib. Nine years after the initiation of targeted therapy, a mass lesion in the esophagus was revealed by follow‐up computed tomography, and endoscopic mucosal resection of the esophageal metastatic lesion was performed. One year later, a bladder tumor was detected by follow‐up computed tomography. The patient underwent transurethral resection of the bladder tumor. Histological evaluation of both resected specimens disclosed clear cell renal cell carcinoma. Conclusion We present a valuable case of metachronous esophagus and bladder metastases from renal cell carcinoma in a long‐term follow‐up.

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A case of gastric metastasis from renal cell cancer during the sequential targeted therapy

Cited by 3 publications

References 14 publications

Giant Abdominal Mass: Papillary Renal Cell Carcinoma with Metastases to the Bladder, Omentum and Perigastric Tissue

Giant Abdominal Mass: Papillary Renal Cell Carcinoma with Metastases to the Bladder, Omentum and Perigastric Tissue

Metastasis to the stomach: a systematic review

Unusual metastasis from renal cell cancer after partial nephrectomy and sequential targeted therapy

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