A case of gastric cancer after sleeve gastrectomy

Yamashita, Takeshi; Tan, Jeremy; Lim, Ee Jean; Eng, Alvin; Ong, Hock Soo; Chan, Weng Hoong

doi:10.1111/ases.12777

Cited by 10 publications

(5 citation statements)

References 10 publications

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“…Finally, 17 patients reported cancer arising in the esophagus or the stomach after SG were found in 15 articles. [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] There were 4 esophageal cancers,4 gastroesophageal cancers and 9 gastric cancers. The characteristics of patients are summarized in Tables 1 and 2.…”

Section: Resultsmentioning

confidence: 99%

Esophagogastric Cancer After Sleeve Gastrectomy: A Systematic Review of Case Reports

Chen¹,

Wang²,

Zhu³

et al. 2021

CMAR

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Introduction: Sleeve gastrectomy (SG) is the most commonly performed bariatric procedure. It has been shown that bariatric surgery reduces cancer risk. However, the risk of esophagogastric cancer after SG has not been defined yet and the development of cancer in the esophagus and stomach remains a matter of concern. Methods: Web of Science, PubMed and Embase databases were searched. Articles that described the diagnosis and management of esophageal or gastric cancer after SG were considered. Results: Seventeen esophagogastric cancer patients after SG were included. The age of the patients ranged from 21 to 64 years. Tumors were diagnosed after an interval of 33.9 ±22.8 months from SG (range 4 months-96 months). There were 4 esophageal cancers,4 gastroesophageal cancers and 9 gastric cancers; adenocarcinoma was the most frequent tumor histology (88.2%). The most commonly reported symptoms were food intolerance/dyspepsia (50.0%), vomiting/nausea/regurgitation (35.7%). Upper gastrointestinal endoscopy (UGIE) with biopsy was used for diagnosis in most of the patients. Surgery was performed in 10 patients (58.8%), while 4 patients were treated by endoscopic procedures (23.5%). The mean follow-up length was 12.2 months (range 3 months-36 months) and the overall disease-free survival rate was 88.9%. Conclusion:The development of esophagogastric cancer after SG is still not well defined but it may occur at any time. Preoperative and follow-up UGIE are essential in order to allow for prevention, early diagnosis. Further epidemiologic studies are needed to investigate the post-SG-related risk of esophagogastric cancer development.

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Section: Resultsmentioning

confidence: 99%

Esophagogastric Cancer After Sleeve Gastrectomy: A Systematic Review of Case Reports

Chen¹,

Wang²,

Zhu³

et al. 2021

CMAR

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“…A pesar de que la incidencia de cáncer postquirúrgico se mantiene baja en occidente y no se realiza EDA rutinariamente 31 , en los países asiáticos, donde hay alta incidencia de cáncer gástrico, la EDA postoperatoria es obligatoria 34 . Algunos autores solamente recomiendan el seguimiento con EDA a pacientes que desarrollan síntomas gastrointestinales tras la GV, como disfagia, pérdida de peso inexplicada, o anemia difícil de tratar, y con factores de riesgo para cáncer 5,14,18,35,36 . A pesar de esto, los síntomas descritos tienden a ser ignorados debido a solapamiento con síntomas atribuidos a la cirugía y el diagnóstico es retrasado 25 .…”

Section: Discussionunclassified

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Parada¹,

Tapia²,

Vidal³

2022

Rev. Cirugia

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Introducción: La obesidad y el índice de masa corporal (IMC) actúan como factores de riesgo para diversas neoplasias, sin una clara relación con el cáncer gástrico no cardial. La cirugía bariátrica es el manejo más efectivo contra la obesidad. La incidencia de cáncer gástrico posterior a la gastrectomía vertical es aún incierta. El primer caso de cáncer gástrico, 4 años posterior a una gastrectomía vertical, se publicó en 2014, y hasta la fecha se han descrito 11 casos en la literatura.Caso clínico: Masculino de 52 años, con antecedente de gastrectomía vertical, presenta cuadro clínico, endoscópico e histopatológico compatible con adenocarcinoma de cuerpo gástrico 5 años posterior a cirugía bariátrica. Recibe tratamiento neoadyuvante con quimioterapia esquema FLOT 6 ciclos, luego gastrectomía total oncológica laparoscópica con disección ganglionar D2 y adyuvancia con esquema FOLFOX 6 ciclos. Estudio histopatológico resulta adenocarcinoma pobremente diferenciado con 90% de regresión tumoral, sin metástasis ganglionar en lo extraído (pT1bN0M0). Seguimiento por 6 meses sin signos clínicos e imagenológicos de recidiva tumoral.Discusión: Existiría una relación directa entre el IMC y cáncer de unión gastroesofágica, la que no ha sido demostrada para cáncer gástrico no cardial. El estudio con endoscopía digestiva alta previo a cirugía bariátrica no está estandarizado, sin embargo, es recomendable realizarlo. La cirugía bariátrica podría disminuir el riesgo de ciertas neoplasias, mientras que la incidencia de cáncer gástrico posterior a dicha cirugía aún no está bien definida. Es recomendable realizar seguimiento endoscópico a los pacientes postoperados de gastrectomía vertical, más aun en sintomáticos.

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“…It can cause erosive esophagitis, barret esophagitis, and gastroesophageal junction cancer (Nilsson and Lagergren, 2004). However, there are also cases with cancer development in the antrum and corpus of the stomach remaining after sleeve gastrectomy (Seki et al, 2018;Vladimirov et al, 2017;Yamashita et al, 2019 (Lee et al, 2017). Endoscopic removal of premalignant lesions after surgery is not possible due to the narrow area.…”

Section: Discussionmentioning

confidence: 99%

“…This retrospective study was conducted at Inonu University General Surgery Clinic in accordance with the ethical standards of the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study protocol was approved by our institutional Ethical Committee (no.2018/ [16][17][18][19]. All patients who underwent sleeve gastrectomy due to obesity between June 2014 and August 2019 at Inonu University Faculty of Medicine General Surgery Clinic were retrospectively reviewed.…”

Section: Methodsmentioning

confidence: 99%

Histopathological findings of gastric specimens of patients undergoing sleeve gastrectomy

Uylaş¹,

Gündoğdu²,

Çiçek³

et al. 2021

JECM

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Sleeve gastrectomy is the most preferred surgical procedure in obese patients. In the literature, the necessity of pathological examination of the specimen is emphasized because of malignant case reports. In this study, we aimed to present the histopathological findings of the specimens of our patients who underwent sleeve gastrectomy due to obesity in the light of the literature. Patients who underwent sleeve gastrectomy due to obesity between 2014-2019 in our clinic were retrospectively screened. Endoscopy was not performed in patients with no symptoms. After the obesity committee, the patients were operated and the specimens were sent for routine histopathological examination. Patients' age, gender, body mass index, surgical procedure information, and histopathological features of resected gastric specimens were analyzed. A total of 411 patients were included in the study and there were 309 (75.2%) female patients. The overall mean age was 35 ± 10.3 and the mean body mass index was 44.7 ± 5.2 kg / m2. The pathology of 85 (20.7%) of the patients were reported as completely normal. Abnormal pathological findings were detected in 326 (79.3%) patients. No malignant finding was found in the specimen pathology results. The necessity of endoscopic examination before sleeve gastrectomy is controversial. Even if no malignant pathological result was detected in our study, we believe that routine pathological examination is required for medicolegal reasons.

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A case of gastric cancer after sleeve gastrectomy

Cited by 10 publications

References 10 publications

Esophagogastric Cancer After Sleeve Gastrectomy: A Systematic Review of Case Reports

Esophagogastric Cancer After Sleeve Gastrectomy: A Systematic Review of Case Reports

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Histopathological findings of gastric specimens of patients undergoing sleeve gastrectomy

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