A case of ganglioneuroma of the ureter and review of the literature

Abstract

Ganglioneuroma is a rare tumor originating from neural crest tissue of the sympathetic nervous system. We report on an approximately 55-year-old woman who was admitted to hospital with abdominal pain. Surgery revealed a tumor in her right ureter, which was pathologically confirmed as a ganglioneuroma. The patient underwent transabdominal total hysterectomy, bilateral adnexal resection, release of pelvic and intestinal adhesions, right ureteroscopy, right ureter retrograde intubation, right ureteral lesion excision, and ureteral anastomosis. A literature review indicated that most ganglioneuromas are benign tumors. Clinicians may consider total or subtotal tumor resection, depending on the tumor location and patient's condition. The patient’s clinical condition may improve after surgery combined with periodic long-term follow-up.

A rare entity: Ganglioneuroma of the prostate

“…They have also been rarely reported in the genitourinary tract. 1 , 2 , 3 , 4 , 5 Per these case reports, genitourinary ganglioneuromas are frequently associated with neurofibromatosis type 1. 1 , 2 , 5 However, as our patient had no history of neurofibromatosis type 1 and no subsequent lesions identified on imaging, we are reporting, to our knowledge, the first instance of ganglioneuroma involving the prostate without a currently identified genetic linkage.…”

A giant lobular thoracic ganglioneuroma cause skeletal erosion: A case report and literature review

“…Typically, GNs present in the retroperitoneum, posterior mediastinum, or adrenal gland, and occasionally in atypical locations such as intracranial and ureter. [1][2][3] GNs are typically oval or round in shape and do not destructively erode surrounding structures. [4] In this report, we describe a unique instance of a gigantic lobular GN in the thoracic cavity that caused neighboring rib deformity and erosion of nearby vertebral bodies.…”