A case of first-onset psychosis and repeated relapses secondary to discontinuation of non-prescription estrogen replacement therapy in a transgendered female

Moffitt, Olivia; Findley, Jonathan Chase

doi:10.1080/09513590.2016.1202230

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…Knowing that low estrogen periods are times of special risk for psychotic episodes is especially useful for secondary prevention (prevention of recurrent episodes of psychosis) in women diagnosed with schizophrenia. Relapse can be prevented by increasing the dose of AP medication at low estrogen times in the menstrual month[ 46 , 47 ], during the postpartum period[ 48 ], after menopause[ 49 , 50 ], whenever therapeutic estrogen is stopped[ 51 , 52 ], or during therapy with anti-estrogen drugs[ 53 , 54 ]. These theoretical examples suggest that effective prevention of schizophrenia may, in the future, be possible in a sex-specific manner[ 55 , 56 ], though this is not the case presently.…”

Section: Potential Prevention Strategiesmentioning

confidence: 99%

Women who suffer from schizophrenia: Critical issues

Seeman

2018

WJP

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Many brain diseases, including schizophrenia, affect men and women unequally - either more or less frequently, or at different times in the life cycle, or to varied degrees of severity. With updates from recent findings, this paper reviews the work of my research group over the last 40 years and underscores issues that remain critical to the optimal care of women with schizophrenia, issues that overlap with, but are not identical to, the cares and concerns of men with the same diagnosis. Clinicians need to be alert not only to the overarching needs of diagnostic groups, but also to the often unique needs of women and men.

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Section: Potential Prevention Strategiesmentioning

confidence: 99%

Women who suffer from schizophrenia: Critical issues

Seeman

2018

WJP

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Estradiol/lorazepam

2017

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Sexual and Reproductive Health in Adolescents and Young Adults With Psychotic Disorders: A Scoping Review

Vickers

Choi

Eriksson

et al. 2022

Schizophrenia Bulletin

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Background and Hypothesis The sexual and reproductive health (SRH) of young people with psychosis has been largely overlooked. We hypothesised that there are key deficiencies in the existing literature on the SRH of adolescents and young adults with psychotic disorders. Study Design We conducted a systematic scoping review using Pubmed, Web of Science, Embase, PsycINFO, and CINAHL. We included empirical studies and case reports focused on SRH issues in young people (aged 14–24 years) with psychotic disorders. A qualitative synthesis was completed. Joanna Briggs Institute Critical Appraisal Tools were utilized to assess study quality. Study Results Seventeen empirical studies and 52 case reports met inclusion criteria. Most focused on sexual dysfunction which was identified as common among this cohort and associated with both psychotic disorders and antipsychotics. The study population was more likely to engage in sexual risk-taking behavior and was at higher risk of sexually transmissible infections than those without psychosis. SRH topics of clinical relevance in older patients with psychosis such as pregnancy, abortion, sexual violence, coercion, sexual identity, and gender were poorly addressed in this younger group. We found empirical studies generally lacked identification and controlling of confounders whilst case reports provided limited description of mental health and SRH outcomes following clinical intervention. Conclusion Research and clinical practice addressing sexual and reproductive health is needed for young people living with psychosis. To address research gaps future studies should focus on women’s health, sexual violence, gender, and sexuality in young people with psychosis.

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A case of first-onset psychosis and repeated relapses secondary to discontinuation of non-prescription estrogen replacement therapy in a transgendered female

Cited by 3 publications

References 12 publications

Women who suffer from schizophrenia: Critical issues

Women who suffer from schizophrenia: Critical issues

Estradiol/lorazepam

Sexual and Reproductive Health in Adolescents and Young Adults With Psychotic Disorders: A Scoping Review

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