A case of familial neurofibromatosis  in pediatric practice

Зрячкин, Н. И.; Бучкова, Т. Н.; Чеботарева, Г. И.; Стяжкина, Н. Б.

doi:10.18786/2072-0505-2018-46-2-200-205

Cited by 2 publications

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“…В случае хронической патологии (ХГД) возникает перераспределение пластических и энергетических ресурсов, направленных на восстановление поврежденной системы, и, как следствие, субоптимальное обеспечение остальных органов и систем с усугублением психоэмоциональных нарушений и закреплением психопатологических черт характера [6]. Этот факт подтверждают данные, что психосоматический компонент соматических заболеваний детей и подростков выявляется практически в 70% случаев [2].…”

Section: Introductionunclassified

“…Этот факт подтверждают данные, что психосоматический компонент соматических заболеваний детей и подростков выявляется практически в 70% случаев [2]. В тоже время, возникающий на фоне ХГД комплекс психоэмоциональных изменений, не только способствует поддержанию хронического воспаления, но и придает ему новую клиническую окраску [6,7]. Это позволяет рассматривать изменения психоэмоционального статуса в качестве дополнительного патогенетического фактора, модифицирующего характер течения основного заболевания, снижающего адаптивные возможности Оригинальные статьи детского организма с последующим ухудшением социальной адаптации и качества жизни детей.…”

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The state of psycho-emotional status in adolescent children with chronic gastroduodenitis, associated with Helicobacter pylori infection in the period of exacerbation and remission

Gurova

2023

APPS

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Relevance. In the pathogenesis of chronic gastroduodenitis, along with an infectious factor (Helicobacter Pylori infection), an important role is played by the state of the patient’s psycho-emotional status, which is characterized by a high incidence of anxiety and subdepressive states in adolescence. Goals: to assess the state of the psycho-emotional status and quality of life in adolescent children with chronic gastroduodenitis associated with Helicobacter pylori infection in the period of exacerbation, after 1 month and 6 months after successful eradication therapy. Materials and methods. The prospective case-control study included 60 adolescent children with morphologically proven chronic gastroduodenitis associated with Helicobacter pylori infection (main group) in the period of exacerbation, in 1 month. and 6 months. after successful eradication therapy. As a comparison group, 22 schoolchildren with the first health group were taken, comparable in age and gender with the children of the main group. All children underwent psychological testing (Spielberger test to assess the levels of reactive and personal anxiety, Zung test to determine the level of depression) and assessed the quality of life. Results. During the period of remission, more than half of the children with chronic gastroduodenitis had complaints common for asthenic syndrome: weakness, mental exhaustion, and headaches. In the period of exacerbation, the highest rates were noted on the scales of personal and reactive anxiety, depression, followed by improvement during treatment and worsening of indicators after 6 months after eradication therapy. Quality of life indicators, characterized by improvement after eradication therapy, after 6 months. showed a statistically significant decrease on the scales of physical functioning (RP), general health (GH), vitality (VT) and mental health (MH). Conclusion: Adolescent children with chronic gastroduodenitis characterized by changes in the psycho-emotional status in the form of subdepression and increased anxiety, both reactive and personal. These changes are not completely stopped after the use of traditional therapy for chronic gastroduodenitis and persist in the period of remission, worsening the quality of life, increasing the negative perception of the disease and treatment prospects.

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Section: Introductionunclassified

The state of psycho-emotional status in adolescent children with chronic gastroduodenitis, associated with Helicobacter pylori infection in the period of exacerbation and remission

Gurova

2023

APPS

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Êë³í³÷íà ïåä³àòð³ÿ / Clinical Pediatrics

ВступНа сьогодні спостерігається невпинне зростання частоти виявлення хронічного гастродуоденіту (ХГД) у дітей всіх вікових груп (110-126 випадків на 1000 дитячого населення), особливо в підлітків (140-150 випадків на 1000 дитячого населення) [1]. Різнома-

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Chronic gastroduodenitis associated with Helicobacter pylori in combination with giardiasis in children

Sorokman

Koliesnik

Popelyuk

2022

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Background. The results of most scientific studies in recent years have made it possible to reconsider the traditional ideas about the pathogenesis of chronic gastroduodenitis (CGD) from a new perspective. The purpose was to investigate the clinical and endoscopic features of СGD associated with Helicobacter pylori (H.pylori) in combination with giardiasis. Materials and methods. The study included 105 children aged 7–16 years divided into two groups: I — patients with СGD associated with H.pylori (n = 29), II — children with СGD associated with H.pylori in combination with giardiasis (n = 76). The study was conducted on the basis of the gastroenterology department of the Chernivtsi Regional Clinical Hospital during 2020–2021 and included esophagogastroduodenofibroscopy, ultrasound examination of the abdominal cavity, rapid urease test, determination of specific M, A and G immunoglobulins to H.pylori CagA antigen in the blood serum and in feces, fecal examination for Giardia lamblia (G.lamblia) antigen by polymerase chain reaction. Results. The most severe infection of G.lamblia occurred in children aged 9–13 years (17 people out of 29 positive). The number of children with G.lamblia increased between the ages of 7–9 and 10–12 years (p < 0.05, χ2 = 5.236, z = 1.899) and decreased in the age of 13–16 years (p < 0.05, χ2 = 7.144, z = 2.567). Patients with giardiasis complained of irritability (p < 0.05), headache, dizziness, restless sleep, heart pain, and they were more likely to show signs of intoxication and skin syndromes. Children of group I were most often diagnosed with corpus gastritis (p < 0.05), antral gastritis (p < 0.05) or pangastritis (p < 0.05) with focal hyperplasia (p < 0.05), and children of group II — with mainly antral gastritis, as well as severe duodenitis (p < 0.05). A characteristic endoscopic feature in children of group II was follicular duodenitis. Inflammatory process in group II significantly more often (p < 0.05) was severe (81.5 %) and active (77.6 %) and was associated with eosinophilic infiltration (51.3 %), microerosions and foci of lymphoid tissue hyperplasia (6.5 %). Conclusions. The clinical course of СGD associated with H.pylori in combination with G.lamblia is characterized by more pronounced dyspeptic symptoms with signs of intoxication and skin syndromes. According to the results of endoscopic examination, patients suffered from СGD associated with H.pylori infection had esophagitis, corpus gastritis, antral gastritis and pangastritis (p < 0.05) significantly more often. Children with G.lamblia invasion had severe follicular duodenitis (p < 0.05).

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A case of familial neurofibromatosis in pediatric practice

Cited by 2 publications

References 0 publications

The state of psycho-emotional status in adolescent children with chronic gastroduodenitis, associated with Helicobacter pylori infection in the period of exacerbation and remission

The state of psycho-emotional status in adolescent children with chronic gastroduodenitis, associated with Helicobacter pylori infection in the period of exacerbation and remission

Chronic gastroduodenitis associated with Helicobacter pylori in combination with giardiasis in children

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