A case of extraosseous intradural osteosarcoma of the spine in a dog

Abstract

A 9.5-year-old labrador presented with signs of progressive C1-C5 myelopathy. Magnetic resonance imaging of the cervical spine revealed a broad-based, jagged and partially ill-defined intradural mass lesion at the level of C3-C4 cervical vertebra. Decompressive spinal surgery was performed and the removed mass was sent for histopathological examination that identified an intradural extraosseous osteosarcoma. This very rare canine spinal tumour appears to arise predominantly in the cervical spine and occurs with no predisposing factors. It should be considered as a differential diagnosis for spinal tumours. CASE PRESENTATIONA 9.5-year-old, female, entire labrador was presented to the Department of Neurology and Neurosurgery with progressive deteriorating neurological deficits over a period of 2 months and a background history of laryngeal paralysis treated withThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Metastatic intradural primary spinal osteosarcoma: illustrative case

“…7 In the literature, there have been five described cases of primary intradural extramedullary osteosarcomas, two of which were cervical lesions in dogs. [7][8][9] Curiously, all three human cases involved the lumbosacral region (Table 1). The first two reported patients were both elderly women, sharing a previous history of iofendylate myelography.…”

Case Series: Computed Tomography Features of Extraskeletal Osteosarcoma in Six Dogs

“…Accounting for 1% of all osteosarcoma cases, exOSA can occur in a variety of organs [ 6 ]. Cases of canine exOSA involving the gastrointestinal tract, subcutaneous tissue, spleen, urinary tract, liver, mediastinum, skin, muscle, eyes, central nervous system, omentum, pericardium, and thyroid gland have been reported [ 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. Additionally, exOSA tends to affect older dogs more frequently than skeletal osteosarcoma, although no predispositions regarding dog size have been reported [ 6 , 7 ].…”