A case of eosinophilic fasciitis without skin manifestations: a case report in a patient with lupus and literature review

Analysis of Peripheral Blood Basophils in Pediatric Systemic Lupus Erythematosus

“…In order to complete the hematological picture, pSLE patients also showed significant reduction in the absolute eosinophil count compared to both JIA and NR children. Most studies providing some information on eosinophil homeostasis in SLE patients are represented by case reports describing its association with some eosinophilic (especially gastro-intestinal) and unusual comorbidities [ 31 , 32 ]. However, we found one study by Yang et al, wherein they analyzed several hematological parameters (including eosinophil count) in different adult autoimmune disorders (including SLE).…”

A 31-Year-Old Man With Bilaterally Limited Mobility of Joints

“…The appearance of orange peel caused by skin induration and the groove sign, which is probably due to the relative sparing of the epidermis and superficial dermis by the fibrotic process, are typical signs of established EF . Occasionally, EF can present without skin involvement . Sclerodactyly and Raynaud phenomenon are usually absent.…”

“…3 Occasionally, EF can present without skin involvement. 6,7 Sclerodactyly and Raynaud phenomenon are usually absent. Laboratory findings of EF include peripheral eosinophilia, increased ESR and CRP level, polyclonal hypergammaglobulinemia, and negative ANA test results.…”

Clues for eosinophilic fasciitis: groove sign and orange peel appearance

“…Eosinophilic fasciitis is a rare fibrosing disorder of muscle fascia of unknown etiology. Clinically, areas of orange peel-like ("pseudo-cellulite") and linear depressions along the course of the superficial veins ("groove sign") are characteristic 1 . This last physical finding is probably due to the relative sparing of the epidermis and superficial dermis around the vessels by the fibrotic process compared to the deep tissue 2 .…”