A case of encephalitis following COVID-19 vaccine

Kobayashi, Yuya; Karasawa, Seishu; Ohashi, Nobuhiko; Yamamoto, Kanji

doi:10.1016/j.jiac.2022.02.009

Cited by 27 publications

(28 citation statements)

References 8 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The overall observed rate of Bell's palsy after vaccination was higher than the expected rates Kobayashi et al (109) 1 case of encephalitis after 1 st dose, exacerbated after 2 nd dose.…”

Section: Razok Et Al (51) 1 Case Of Gbs Presenting After 2 Nd Vaccinementioning

confidence: 69%

“…In addition, a case report of a Japanese lady admitted who developed diplopia the next day following the first dose of the BNT162b2 vaccine administration was described in the literature ( 109 ). The symptoms aggravated after the second dose of the vaccine and the patients was finally diagnosed with encephalitis based on brain MRI findings.…”

Section: Autoimmune Adverse Events Following Immunization and Their C...mentioning

confidence: 99%

See 1 more Smart Citation

COVID-19 Vaccination and the Rate of Immune and Autoimmune Adverse Events Following Immunization: Insights From a Narrative Literature Review

et al. 2022

View full text Add to dashboard Cite

Despite their proven efficacy and huge contribution to the health of humankind, vaccines continue to be a source of concern for some individuals around the world. Vaccinations against COVID-19 increased the number of distressed people and intensified their distrust, particularly as the pandemic was still emerging and the populations were encouraged to be vaccinated under various slogans like “back to normal life” and “stop coronavirus”, goals which are still to be achieved. As fear of vaccination-related adverse events following immunization (AEFIs) is the main reason for vaccine hesitancy, we reviewed immune and autoimmune AEFIs in particular, though very rare, as the most worrisome aspect of the vaccines. Among others, autoimmune AEFIs of the most commonly administered COVID-19 vaccines include neurological ones such as Guillain-Barre syndrome, transverse myelitis, and Bell’s palsy, as well as myocarditis. In addition, the newly introduced notion related to COVID-19 vaccines, “vaccine-induced immune thrombotic thrombocytopenia/vaccine-induced prothrombotic immune thrombotic thrombocytopenia” (VITT/VIPITT)”, is of importance as well. Overviewing recent medical literature while focusing on the major immune and autoimmune AEFIs, demonstrating their rate of occurrence, presenting the cases reported, and their link to the specific type of COVID-19 vaccines represented the main aim of our work. In this narrative review, we illustrate the different vaccine types in current use, their associated immune and autoimmune AEFIs, with a focus on the 3 main COVID-19 vaccines (BNT162b2, mRNA-1273, and ChAdOx1). While the rate of AEFIs is extremely low, addressing the issue in this manner, in our opinion, is the best strategy for coping with vaccine hesitancy.

show abstract

“…The overall observed rate of Bell's palsy after vaccination was higher than the expected rates Kobayashi et al (109) 1 case of encephalitis after 1 st dose, exacerbated after 2 nd dose.…”

Section: Razok Et Al (51) 1 Case Of Gbs Presenting After 2 Nd Vaccinementioning

confidence: 69%

Section: Autoimmune Adverse Events Following Immunization and Their C...mentioning

confidence: 99%

COVID-19 Vaccination and the Rate of Immune and Autoimmune Adverse Events Following Immunization: Insights From a Narrative Literature Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…

We read with interest the article by Kobayashi et al, (2022). about a 46 years-old female who developed a focus disorder one day after having received her first dose of the anti-SARS-CoV-2 vaccine BNT162b2 (Biontech Pfizer vaccine (BPV)) (Kobayashi, Y. et al, 2022). Since the second day after vaccination she developed permanent, fluctuating diplopia (Kobayashi, Y. et al, 2022).

…”

mentioning

confidence: 99%

“…about a 46 years-old female who developed a focus disorder one day after having received her first dose of the anti-SARS-CoV-2 vaccine BNT162b2 (Biontech Pfizer vaccine (BPV)) (Kobayashi, Y. et al, 2022). Since the second day after vaccination she developed permanent, fluctuating diplopia (Kobayashi, Y. et al, 2022). After the second dose, three weeks after the first one, diplopia worsened again (Kobayashi, Y. et al, 2022).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Encephalitis As a Complication of SARS-CoV-2 Vaccines Is More Common Than Previously Thought

Finsterer¹,

Matovu²

2022

IARJMS

View full text Add to dashboard Cite

show abstract

Seronegative acute encephalitis following COVID-19 vaccines: a case series of an overlooked diagnosis with literature review

Mansour,

Chadli,

Ghachem

et al. 2023

Eur J Clin Pharmacol

View full text Add to dashboard Cite

Purpose Autoimmune encephalitis is a neurological emergency of new-onset altered mental status, caused by an exaggerated immune-mediated response that targets the central nervous system. Autoimmune encephalitis has become an emerging differential diagnosis, when a classical infection cannot explain neurological symptoms. Displaying overlapping clinical presentations, ranging from the insidious onset of cognitive deficiency to more severe forms of encephalopathy with refractory seizures, autoimmune encephalitis can be challenging for clinicians. When evidence of malignancy is absent and pathogenic autoantibodies are undetected, with typical clinical and imaging features of autoimmune encephalitis, seronegative autoimmune encephalitis may be considered. Recently, vaccination-related autoimmune encephalitis and acute encephalitis after COVID-19 vaccination have attracted attention. Methods and results We report a case series consisting of three patients with autoimmune encephalitis occurring shortly after COVID-19 vaccination and a current review of all previous reported autoimmune encephalitis related to COVID-19 vaccines. Conclusion We emphasise on the prompt diagnosis of autoimmune encephalitis induced by Covid-19 vaccines and its timely treatment to improve the clinical outcome of this severe neurological condition. Post-licencing vaccine safety surveillance for potential adverse events is essential for vaccine safety and public confidence.

show abstract

A case of encephalitis following COVID-19 vaccine

Cited by 27 publications

References 8 publications

COVID-19 Vaccination and the Rate of Immune and Autoimmune Adverse Events Following Immunization: Insights From a Narrative Literature Review

COVID-19 Vaccination and the Rate of Immune and Autoimmune Adverse Events Following Immunization: Insights From a Narrative Literature Review

Encephalitis As a Complication of SARS-CoV-2 Vaccines Is More Common Than Previously Thought

Seronegative acute encephalitis following COVID-19 vaccines: a case series of an overlooked diagnosis with literature review

Contact Info

Product

Resources

About