A Case of Early Rectal Cancer Associated with von Willebrand Disease Cured by Laparoscopic Low Anterior Resection

Abstract

A 46-year-old man who had been diagnosed with von Willebrand disease consulted our hospital because of diarrhea and melena. Several examinations revealed a submucosal rectal tumor and early rectal cancer. Further investigation revealed type 2A von Willebrand disease and a slightly prolonged activated partial thromboplastin time. Using activated partial thromboplastin time as an index, we administered blood clotting factor Ⅷ /von Willebrand factor concentrate, and performed local excision and endoscopic submucosal dissection of the rectal tumor. For additional bowel resection, laparoscopic low anterior resection was performed. Thus, we safely performed laparoscopic low anterior resection in a patient with von Willebrand disease by supplying factor Ⅷ /von Willebrand factor concentrate. Key words：von Willebrand disease，rectal cancer，laparoscopic surgery