A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue

Shin, Young Kook; Kwon, Joong Goo; Kim, Ka Young; Park, Jae Bum; Han, Seok Jae; Cheon, Jong Woon; Kim, Eun Young Ariel; Kim, Ho Gak; Lee, Tae Sung; Park, Kyung Sik; Won, Kyoung Sook

doi:10.5056/jnm.2010.16.1.77

Cited by 12 publications

(10 citation statements)

References 21 publications

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“…Other therapies demonstrating successful CVS treatment in case reports and case series include chlorpromazine, 37 gonadotropin releasing hormone analogue, 38 mirtazapine, 39 onabotulinumtoxinA, 40 and risperidone. 41 …”

Section: Refractory Patientsmentioning

confidence: 99%

Cyclic vomiting syndrome: diagnostic approach and current management strategies

Hayes¹,

VanGilder²,

Berendse³

et al. 2018

CEG

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Cyclic vomiting syndrome (CVS) is a disorder characterized by episodes of nausea and vomiting lasting for 1–5 days followed by asymptomatic periods. The etiology of CVS is unknown, but it shares similar characteristics to migraine headaches. CVS is generally classified as having four phases: prodromal, acute/vomiting/hyperemesis, recovery, and remission/interepisodic. Current management strategies include trigger avoidance, abortive and prophylactic medication therapies, and supportive care. The goal of therapy for the remission phase is prophylaxis of further episodes. Antidepressant, antiepileptic, and antimigraine medications show an overall reduction or remission of CVS symptoms in more than 70% of patients. This article provides a summary of diagnostic strategies and reviews current management strategies for CVS.

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Section: Refractory Patientsmentioning

confidence: 99%

Cyclic vomiting syndrome: diagnostic approach and current management strategies

Hayes¹,

VanGilder²,

Berendse³

et al. 2018

CEG

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“…Multiple triggering factors have been proposed for acute emetic episodes. Some of these factors are respiratory infections (upper respiratory tract infections and chronic sinusitis), emotional stress, motion sickness, insomnia, severe physical activity, certain food products (cacao, cheese), and menstruation in some women [ 5 ]. Cyclic vomiting syndrome was primarily described in children, but it may be diagnosed at any age [ 6 – 8 ].…”

Section: Introductionmentioning

confidence: 99%

The efficacy and duration of treatment with propranolol in children with cyclic vomiting syndrome in southern Iran

Haghighat¹,

Memari²,

Honar³

et al. 2017

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IntroductionCyclic vomiting syndrome is a functional disorder characterised by repeated episodes of nausea and vomiting with symptom-free intervals between the attacks. Cyclic vomiting syndrome is a migraine equivalent; therefore, anti-migraine medications are effective for cyclic vomiting syndrome prophylaxis, but duration of treatment is not clear.AimTo determine the efficacy and duration of drug therapy in cyclic vomiting syndrome.Material and methodsThis study was conducted on 206 cases of cyclic vomiting syndrome, who were treated with propranolol as prophylaxis. After they were symptom-free for at least 9 months, propranolol was tapered and discontinued and then they were followed for at least 6 months after drug withdrawal for evaluation of recurrence.ResultsThe study subjects included 127 boys and 79 girls. The mean age of symptom onset was 3.4 years (range: 3 months to 14.5 years) and the mean age at the time of diagnosis was 5.7 years (range: 8.4 months to 18 years). Among the 206 patients in whom propranolol was discontinued, only 16 (7.8%) subjects developed recurrence of symptoms in the 6-month follow-up period.ConclusionsThere is no need to continue prophylaxis of cyclic vomiting syndrome for a long time. It is also possible to make the duration of drug therapy shorter, which is useful for the convenience of the patients and prevention of drug side effects.

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“…CV episodes in children cease spontaneously before puberty in most cases, but persistence to adult life is well acknowledged. CVS in adults can occur at any age, with an average onset age of 21 to 35 in limited case series [8]. Although the clinical features in each age group are similar [9]; some differences in symptoms profile, pathogenesis and associated comorbidities have been observed between adults and children [1].…”

Section: Discussionmentioning

confidence: 99%

Catamenial cyclic vomiting syndrome responding to Oestrogen therapy: an adolescent case report

et al. 2019

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Cyclic vomiting syndrome (CVS) is defined by episodes of vomiting lasting from a few hours to several days, alternating with periods of no symptoms. Various symptoms can be associated with vomiting such as nausea, migraine or abdominal pain. Common triggers of CVS include infection, psychological stress and menstruation. CVS's diagnosis requires exclusion of alternative diseases particularly neurological and gastrointestinal. CVS shares many common features with catamenial migraine including treatment. We herein report a case of CVS in a 16 years old girl characterized by stereotypical vomiting attacks occurring in every menstrual period. Recurrent vomiting episodes began 2 years before admission. Given the negativity of paraclinical exams and the absence of response to different therapeutic approaches as well as the similarity with catamenial migraine, we treated our patient with permenstrual percutaneous oestrogen for six months. The evolution was marked by the disappearance of symptoms within the first month and the absence of their recurrence after treatment cessation during a follow-up of 6 years.

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A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue

Cited by 12 publications

References 21 publications

Cyclic vomiting syndrome: diagnostic approach and current management strategies

Cyclic vomiting syndrome: diagnostic approach and current management strategies

The efficacy and duration of treatment with propranolol in children with cyclic vomiting syndrome in southern Iran

Catamenial cyclic vomiting syndrome responding to Oestrogen therapy: an adolescent case report

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