A case of cutaneous pseudolymphoma with a distinctive appearance treated successfully by intralesional interferon alpha‐1b and corticosteroids

Abstract

Cutaneous pseudolymphoma (CPL) encompasses various forms of benign lymphocytic proliferative dermatoses that mimic the clinical and/or pathological changes of lymphoma. The clinical manifestations of CPL vary due to differences in the pathogenesis, and accordingly, no specific treatment has been identified. Here, we report a case of CPL on the nose, which had a distinctive appearance and was treated successfully using a combination of intralesional interferon alpha‐1b and compound betamethasone (betamethasone sodium phosphate and betamethasone dipropionate). This combination may be a good option for localized CPLs at particular anatomical sites.

A case of multiple nodular cutaneous B‐cell pseudolymphoma successfully treated with glucocorticoid, methotrexate, and hydroxychloroquine

“…Surgical removal is the first choice for solitary CPL in a non‐specific location 10 . Alternative treatment includes topical glucocorticoid, imiquimod, or tacrolimus, intralesional glucocorticoid or interferon, systemic agents, and physical modalities such as laser therapy, cryosurgery, local radiation therapy, and photodynamic therapy 11,12 . For multifocal form, as our patients, systemic agents including glucocorticoid, methotrexate, hydroxychloroquine, and thalidomide can be prescribed 1 .…”

Combined therapy of local recombinant human interferon α1b injection and acupuncture on verruca vulgaris: a retrospective study

“…To obtain higher local concentration, intralesional injection has also been tried. Zeng et al reported a successful case of cutaneous pseudolymphoma on the nose with combination of intralesional IFNα1b and compound betamethasone [ 10 ].…”