A case of COVID-19 patient with the diarrhea as initial symptom and literature review

Yang, Xiaodong; Zhao, Jie; Qiang, Yan; Zhang, Shangxin; Wang, Yi-Gao; Li, Yongxiang

doi:10.1016/j.clinre.2020.03.013

Cited by 33 publications

(29 citation statements)

References 15 publications

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“…13,14 Our findings may contribute to understanding of Covid-19 transmission and the importance of GI disorders as one of the primary symptoms of the disease. 11,[13][14][15] The case fatality rate in this series was 41.7%, as had been reported in critically patients in Seattle and China 9,16 . The age of dead patients was significantly higher than that of the survivors, with a mean of 59.4 years being 62.5% male and with some comorbidity in 52.1% of the cases.…”

Section: Discussionsupporting

confidence: 79%

Clinical characteristics of Covid-19 cases in Guayaquil, Ecuador

Bravo-Acosta¹,

Méndez²

2020

JHVRV

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Introduction: Until April 20 in Ecuador there were 10,122 confirmed cases of Covid-19 with 507 deaths. We described the clinical characteristics of 115 confirmed Covid-19 cases. Methods: Nasopharyngeal swab or tracheal aspirate samples were collected to perform a confirmatory test for Covid-19. Clinical, laboratory and chest radiography data, invasive mechanical ventilation, days of hospitalization and number of deaths were recorded. Results: The mean was 54.1 years with 59% male. 96.5% had Dyspnea being the most frequent symptom and 20% had diarrhea. Hypertension and Diabetes Mellitus were the main comorbidities. The mean until death was 15.3 days with 9.2 days of hospitalization. 40.9% required invasive mechanical ventilation. 48.7% recovered, 9.6% remain hospitalized and 41.7% died. X-ray showed bilateral opacity. 46.9% had leukocytosis and 85.5% of the deceased presented lymphopenia versus 53.7% of the survivors (p<0.001). 77.4% with prolonged prothrombin time and 82.6% elevated lactic dehydrogenase. Discussion: Respiratory symptoms are the most frequent. However, the presence of diarrhea was greater than previously reported suggesting the importance of investigating gastrointestinal disorder as the primary symptom. The fatality rate was 41.7%, like critically ill patients. The age of the deceased was older than the survivors, being 62.5% male and 52.1% with some comorbidity, both considered risk factors for severe forms of Covid-19. Lymphopenia is a critical factor associated with severity and mortality.

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Section: Discussionsupporting

confidence: 79%

Clinical characteristics of Covid-19 cases in Guayaquil, Ecuador

Bravo-Acosta¹,

Méndez²

2020

JHVRV

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“…Diarrhea is the most common GI symptom reported and may be considered as an initial symptom in some infected patients ( D'Amico, Baumgart, Danese, & Peyrin-Biroulet, 2020 ; Yang, Zhao, et al, 2020 ). In comparison with adults in whom decreased appetite is prominent, vomiting is more prominent in children.…”

Section: Discussionmentioning

confidence: 99%

Clinical Manifestations of Gastrointestinal Symptoms in COVID-19 Patients

Abbasinia

Hormati

Hossaini

et al. 2021

Gastroenterology Nursing

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After the outbreak of novel coronavirus disease 2019 (COVID-19) in Wuhan, China, its spread to other countries is rapidly increasing. In this integrative review, we report the prevalence of gastrointestinal symptoms in patients with COVID-19. For this purpose, available articles on gastrointestinal manifestations in patients with COVID-19, which were reported from China, were reviewed. All reviewed articles were searched from December 11, 2019, to June 20, 2020, based on specific key words. Related findings in these articles show that the main target of COVID-19 is lung tissue, as after the virus enters the body, it mainly causes respiratory symptoms in affected patients. But in addition to respiratory symptoms, it is possible that, over time, these patients present with other symptoms, the most obvious of which are gastrointestinal symptoms. It is well documented that diarrhea and vomiting are the most common gastrointestinal symptoms in COVID-19 patients. As part of this report, we also look at the incidence and frequency of gastrointestinal symptoms in COVID-19 patients in Iran. The results can be used by providers as a guideline for better management of gastrointestinal symptoms in these patients.

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“…Three case reports included hematochezia as a symptom [17][18][19]. There are also several case reports that describe patients that present with only GI symptoms initially or throughout the course of their entire infection [20][21][22][23][24]. The largest study, a single-center study by Luo et al found that of 1141 confirmed cases of COVID-19, 16% presented with only GI symptoms [25].…”

Section: Incidental Covid-19 Findings Based On Abdominal Computed Tommentioning

confidence: 99%

Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review

2020

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Purpose This scoping review evaluated the currently available data related to abdominal imaging in the SARS-CoV-2 infection. Method A systematic review of MEDLINE, EMBASE, SCOPUS, and Web of Science was performed from inception to July 15, 2020 using PRISMA-ScR guidelines. The review included case reports and series discussing radiologic manifestations of SARS-CoV-2 infection in abdominal imaging studies.

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A case of COVID-19 patient with the diarrhea as initial symptom and literature review

Cited by 33 publications

References 15 publications

Clinical characteristics of Covid-19 cases in Guayaquil, Ecuador

Clinical characteristics of Covid-19 cases in Guayaquil, Ecuador

Clinical Manifestations of Gastrointestinal Symptoms in COVID-19 Patients

Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review

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