A case of COVID-19 in a patient with a univentricular heart post total cavopulmonary connection (Fontan) surgery

Linnane, Niall; Cox, D.; James, Adam

doi:10.1017/s1047951120001882

Cited by 6 publications

(7 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is the first reported case, to our knowledge, of an infant with functionally univentricular heart disease and parallel circulation with symptomatic Covid-19. Two previous cases of those with functionally univentricular hearts have been reported although these patients had already undergone Fontan and no longer had parallel circulation [4,5]. There are multiple interesting takeaways from this case.…”

Section: Discussionmentioning

confidence: 76%

“…Indeed, some of the children reported to have Covid-19 have been documented to have cardiac disease, but none with functionally univentricular heart disease and parallel circulation (wherein the ascending aortic saturation and pulmonary artery saturations are equal) have been described yet to our knowledge [1][2][3]. Two cases of those with functionally univentricular hearts have been described but these patients had already undergone Fontan palliation and no longer had parallel circulation [4,5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Covid-19 in an infant with systemic to pulmonary artery shunt dependent functionally univentricular physiology

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Covid-19 in an infant with systemic to pulmonary artery shunt dependent functionally univentricular physiology

et al. 2020

View full text Add to dashboard Cite

show abstract

“…After the exclusion of duplicates, 12 articles were selected for inclusion into the analysis (Fig 1). [11][12][13][14][15][16][17][18][19][20][21][22] These comprised a total of 143 patients, of which 99 had CHDs. The key information from each article is summarised in Table 2.…”

Section: Resultsmentioning

confidence: 99%

“…At the time of publication, one patient was discharged and the remaining two were still receiving hospital care. 11,13,16 Based on these numbers and outcomes described, it can be seen that patients with underlying CHD are more likely to develop complications than the overall population; however, 82% of patients recovered and were discharged within 10-20 days.…”

Section: Categorymentioning

confidence: 99%

COVID-19 and congenital heart disease: an insight of pathophysiology and associated risks

et al. 2020

View full text Add to dashboard Cite

Objective: We aimed to examine the literature to determine if both paediatric and adult patients diagnosed with congenital heart disease (CHD) are at a higher risk of poor outcomes if they have the coronavirus disease 2019 (COVID-19), compared to those without CHD. Methods: A systematic review was executed using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. To identify articles related to COVID-19 and CHD, an extensive literature search was performed on EMBASE, Medline, Scopus, and Global Health databases using keywords and MeSH terms. Results: A total of 12 articles met the inclusion criteria and were included for analysis in this systematic review. Two themes were identified for data extraction: evidence supporting higher risks in CHD patients and evidence against higher risks in CHD patients. After combining the data, there were 99 patients with CHDs out of which 12 required admissions to ICU. Conclusion: This systematic review suggests that CHD may increase the risk of poor outcomes for those with COVID-19, but also highlights the necessity for more research with larger sample sizes in order to make a more justified conclusion, as the majority of papers that were analysed were case series and case reports. Future research should aim to quantify the risks if possible whilst accounting for various confounding factors such as age and treatment history.

show abstract

“…At the last follow up point, three patients were discharged and one was still hospitalized. [30][31][32][33] Bezerra et al reported that one female patient was diagnosed with COVID-19 infection after a Fontan procedure for hypoplastic left heart syndrome. Despite the patient was admitted to the ICU and experiencing multiple pulmonary combined with other complications, she was fully recovered and discharged.…”

Section: Overview Of Case Reports In the Literaturementioning

confidence: 99%

Effect of COVID-19 on congenital heart disease children: a literature review

Ali

Alkhuzaie

Alhashim

et al. 2021

Int J Community Med Public Health

View full text Add to dashboard Cite

Congenital heart diseases are the most common birth defects and have variable levels of severity. Some studies showed that CHD increases the odds of COVID-19 realted complications; however, others suggested that there is no such a correlation. Due to the aforementioned lack of evidence, we aim in this review to provide a comprehensive overview of the impact of COVID-19 infection on CHD patients. For that, an extensive literature search of Medline, Cochrane, and EMBASE databases was performed using the medical subject headings or a combination of all possible related terms. Patients diagnosed with both CHD and COVID-19 infection has reported that CHD patients, especially those with a genetic syndrome, are at high risk to develop moderate to severe symptoms. Moreover, CHD surgeries were postponed or even canceled, with a decline in overall admission days, due to hospital protocol or pateints’ decisions. Also, the findings suggested that congenital heart surgeries can be safely done during the pandemic when there is case volume limitation, with the safety precautions are followed by both surgical staff and patients. In conclusion, the scarce evidence along with the variety in CHD types and their different clinical presentations; makes it hard to predict the outcomes and to manage CHD-COVID-19 co-morbid children. More studies are needed to guide management plans in this particular context.

show abstract

A case of COVID-19 in a patient with a univentricular heart post total cavopulmonary connection (Fontan) surgery

Cited by 6 publications

References 6 publications

Covid-19 in an infant with systemic to pulmonary artery shunt dependent functionally univentricular physiology

Covid-19 in an infant with systemic to pulmonary artery shunt dependent functionally univentricular physiology

COVID-19 and congenital heart disease: an insight of pathophysiology and associated risks

Effect of COVID-19 on congenital heart disease children: a literature review

Contact Info

Product

Resources

About