A case of Cotard's Syndrome successfully treated with aripiprazole monotherapy

Berardis, Domenico De; Serroni, Nicola; Campanella, Daniela; Marasco, Viviana; Moschetta, Francesco Saverio; Giannantonio, Massimo Di

doi:10.1016/j.pnpbp.2010.06.015

Cited by 17 publications

(5 citation statements)

References 5 publications

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“…Many patients deny having memories or feelings. Some deny having any thought at all (‘If I had a brain I would think, but I do not think’ (Ross, )) or even a mind (‘I don't have a mind’ (Berardis et al , )).…”

Section: The Cotard Syndromementioning

confidence: 99%

Making Sense of the Cotard Syndrome: Insights from the Study of Depersonalisation

Billon

2016

Mind & Language

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Patients suffering from the Cotard syndrome can deny being alive, having guts, thinking or even existing. They can also complain that the world or time have ceased to exist. In this paper, I argue that even though the leading neurocognitive accounts have difficulties meeting that task, we should, and we can, make sense of these bizarre delusions. To that effect, I draw on the close connection between the Cotard syndrome and a more common (and better studied) condition known as depersonalisation. Even though they are not delusional, depersonalised patients seem to have experiences that are quite similar to those of Cotard patients. I argue that these experiences are essentially characterised by a (more or less important) lack of subjective character and of two other structural features of experience, which I call 'the present character' and 'the actual character.' Cotard's nihilistic delusions simply consist in taking these anomalous experiences at face value.

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Section: The Cotard Syndromementioning

confidence: 99%

Making Sense of the Cotard Syndrome: Insights from the Study of Depersonalisation

Billon

2016

Mind & Language

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“…The most commonly recommended treatment strategy is electroconvulsive therapy (ECT) 4,[15][16][17][18] . But there are several reports of successful treatment with single or combined pharmacotherapy methods.…”

Section: Discussionmentioning

confidence: 99%

Bipolar Disorder and Cotard’s Syndrome-A Case Report and Review

Senjam¹,

Devi²,

Singh³

2014

IOSRJDMS

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“…Antipsychotics are mostly prescribed in combination with antidepressants (Chan et al, 2009; Chou et al, 2011; De Berardis et al, 2015; Kuo and Chou, 2017). However, aripiprazole and sulpiride have been used as monotherapy to successfully treat individuals with Cotard syndrome (De Berardis et al, 2010; Shiraishi et al, 2004). Aripiprazole's indirect facilitation of dopamine transmission through 5-HT receptor–mediated pathways may be involved in its therapeutic effect against the depressive symptoms of Cotard syndrome (Li et al, 2004).…”

Section: Management and Treatmentmentioning

confidence: 99%

Can Cotard Syndrome Be Induced?

et al. 2023

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Cotard syndrome is a rare condition characterized by delusions ranging from a belief that one has lost organs to insisting that one has lost one's soul or is dead. This is the report a case of a 45-year-old man who was comatose after an attempted suicide. This was initially diagnosed as brain death and use of his organs for transplantation was actively considered. However, he awakened days later with new-onset Cotard syndrome. It remains difficult to know the link, unconscious or conscious, between this patient's delusions and the fleeting intention of doctors who intended to transplant his organs. This is the first description of a coincidence between delusional denial of an organ and the potential medico-surgical act of having an organ removed. This case is an opportunity to revisit the philosophical concepts of negation and nihilism. A multidisciplinary reflection is needed to give meaning to other clinical presentations.

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A case of Cotard's Syndrome successfully treated with aripiprazole monotherapy

Cited by 17 publications

References 5 publications

Making Sense of the Cotard Syndrome: Insights from the Study of Depersonalisation

Making Sense of the Cotard Syndrome: Insights from the Study of Depersonalisation

Bipolar Disorder and Cotard’s Syndrome-A Case Report and Review

Can Cotard Syndrome Be Induced?

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