A Case of Corynebacterium Striatum Disseminated Infection and Pneumonia in a Patient With Relapsed Acute Myeloid Leukemia

Guy, Brent; O'Loghlen, Sean; Petriw, L; Heffernan, Paul; Martínez-Cajas, Jorge L

doi:10.1016/j.chest.2016.08.206

Cited by 3 publications

(2 citation statements)

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“…9 Infections with C. striatum have been reported in patients with indwelling catheters and the immunocompromised. 8 We identified three case reports of C. striatum infections complicating cases of leukaemia, [9][10][11] of which one was of AML. 10 COVID-19 is increasingly reported in people with haematological malignancies 12 13 but we believe this is the first reported case of C. striatum infection along with likely COVID-19 in a patient with AML.…”

Section: Discussionmentioning

confidence: 99%

Unusual source of recurrent Corynebacterium bacteraemia in an immunocompromised patient

Bakhsh

2021

BMJ Case Rep

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We describe a unique case of a patient with acute myeloid leukaemia (AML), with recurring infections during chemotherapy from chronic nasal carriage of non-diphtherial Corynebacterium, who was eventually diagnosed as she presented with neutropaenic sepsis. Identifying (often multiple) sources of infection in immunocompromised patients is crucial but deciding whether multiple organisms, which in health are considered as commensals, are actually pathogenic during vulnerable states—can be clinically difficult. Our case highlights the efforts to correctly identify the actual source of this rare organism and the recognition of its pathogenic potential when other illnesses present. We also review the literature of Corynebacteria in patients with haematological malignancies but believe this is the first case of AML to be infected with Corynebacterium presenting during the COVID-19 pandemic with a probable incidental positive swab for SARS-CoV-2.

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Section: Discussionmentioning

confidence: 99%

Unusual source of recurrent Corynebacterium bacteraemia in an immunocompromised patient

Bakhsh

2021

BMJ Case Rep

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“…were described in the literature. They presented as mild airway erythema, circumferential ulcerations, pseudomembranous plaque-like lesions, and severe obstruction of the trachea (28,29,122).…”

Section: Bronchoscopic Findings In Bacterial Caoimentioning

confidence: 99%

Infections causing central airway obstruction: role of bronchoscopy in diagnosis and management

Keshishyan¹,

DeLorenzo²,

Hammoud³

et al. 2017

J. Thorac. Dis.

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Central airway obstructive infections (CAOI) are challenging medical conditions that may represent an advanced and complicated process of ongoing infections. The epidemiology of CAOI is unknown as well as the pathophysiology and the mechanism of development. This is due to sparse data in the literature that consists mainly of case reports and retrospective case series. CAOI can be caused by fungal, bacterial, parasitic and viral infections. Most patients with CAOI can be diagnosed clinically and with chest imaging, which demonstrate obstruction of the central airways. However, bronchoscopy is commonly used to confirm and obtain a specific diagnosis to guide specific therapy. In recent years, interventional pulmonology (IP) is becoming widely available and offer a minimally invasive approach for the management of central airway diseases such as cancers, benign strictures, and other conditions. Various bronchoscopic modalities are used to treat central airway obstruction (CAO), such as mechanical debulking, endobronchial laser therapy, electrocautery, argon plasma coagulation, cryotherapy, and airway stenting. In patients with CAOI, the role of therapeutic bronchoscopy is not clearly defined, but many isolated reports in the literature described bronchoscopic intervention in combination with medical therapy as the initial management approach. In this paper, we present cases of CAOI that underwent bronchoscopic intervention as part of their management. We described the infectious etiology, locations, bronchoscopic findings and bronchoscopic modalities for airway management.

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Diyabetik ayak yaralarında nadir bir etmen: Corynebacterium striatum

Yılmaz

Çetin

Duran

2018

Cukurova Medical Journal

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A Case of Corynebacterium Striatum Disseminated Infection and Pneumonia in a Patient With Relapsed Acute Myeloid Leukemia

Cited by 3 publications

References 0 publications

Unusual source of recurrent Corynebacterium bacteraemia in an immunocompromised patient

Unusual source of recurrent Corynebacterium bacteraemia in an immunocompromised patient

Infections causing central airway obstruction: role of bronchoscopy in diagnosis and management

Diyabetik ayak yaralarında nadir bir etmen: Corynebacterium striatum

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