A case of conus medullaris teratoma

Lekgabe, Ernest; Rogers, Te Whiti; Laidlaw, John D.; Lui, Elaine; Gaillard, Frank

doi:10.1016/j.jocn.2017.09.025

Cited by 4 publications

(7 citation statements)

References 5 publications

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“…No sex spe cific dif fer ences were found in spi nal teratoma in ci dence [4] but there is a sig nif icant dif fer ence in mean age at the time of di ag no sis between male and fe male: 36.4±12.3 years for men and 41.3±11.6 for women [4]. Spi nal teratomas usu ally are not di ag nosed pre op er a tively due to their rar ity [1,10].…”

Section: Discussionmentioning

confidence: 97%

“…Teratoma rarely oc curs in the cen tral ner vous sys tem (only 2% of all teratomas) [5] and it con sti tutes only 0.1-0.5% of all spi nal cord tu mors [2,[4][5][6][7]. More over, teratoma pre dom i nantly oc curs in ne o nates and young chil dren; adult-on set teratoma is very rare [2,3,5,[8][9][10]. To our knowl edge, under 150 cases of adult-on set spi nal teratoma have been reported to this date.…”

Section: Discussionmentioning

confidence: 99%

“…Spi nal teratomas are clas sified into 3 types ac cord ing to the de gree of dif fer en ti a tion: ma ture, im ma ture and ma lig nant [1,23,36]. Histologically ma ture teratoma pres ents with rec og niz ably dif fer en ti ated tis sues [10]. Im ma ture teratomas are com posed of prim itive, un dif fer en ti ated com po nents [10].…”

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

“…Histologically ma ture teratoma pres ents with rec og niz ably dif fer en ti ated tis sues [10]. Im ma ture teratomas are com posed of prim itive, un dif fer en ti ated com po nents [10]. This type of teratoma is prone to fre quent re cur rence and ag gres siveness [1].…”

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

“…Ma lig nant teratomas are de rived from endodermal si nus or yolk sack and may be as so ci ated with a poor prog no sis, es pe cially along with high lev els of se rum E-fetoprotein [25,28]. All teratomas have ma lig nant poten tial, in clud ing ma ture teratomas, in which malignization may arise from squamous com po nents [10].…”

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

See 4 more Smart Citations

Adult-onset spinal teratoma: a case report and review

Blank¹,

Terbetas²,

Neverauskiene³

et al. 2019

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Teratoma yra apibrėžiama kaip neoplazma, kuri susideda iš įvairių parenchiminių ląstelių, kilusių iš trijų germinacinių sluoksnių (ektodermos, mezodermos ir endodermos). Nugaros smegenų teratomos sudaro 0,1–0,5 % visų nugaros smegenų navikų. Taip pat šis navikas yra itin retas tarp suaugusiųjų. Intramedulinė spinalinė teratoma yra pats dažniausias šio naviko tipas. Pagrindiniai spinalinės teratomos požymiai yra skausmas, kojų silpnumas ir tirpimas, šlaplės ar išangės raukų jos sutrikimas, kai anksti pasireiškia sustiprėję refleksai ir šlapinimosi bei tuštinimosi kontrolės praradimas. Histologinis ištyrimas yra tikslios diagnozės nustatymo auksinis standartas. Teratoma diagnozuojama, stebint audinius, kilusius iš visų trijų germinacinių sluoksnių. Magnetinio rezonanso tyrimas yra auksinis diagnostikos standartas. Dėl naviko audinių įvairovės, MRT vaizduose stebimi nehomogeniško intensyvumo vaizdai T1 ir T2 sekose. Chirurginė rezekcija yra pirmo pasirinkimo gydymas šiam navikui ir dažniausiai atliekama laminektomijos metu. Operacijos tikslas daugeliu atvejų turėtų būti radikali rezekcija su nervų kompresijos sumažinimu, siekiant sumažinti neurologinių funkcijų pablogėjimą. Straipsnio autoriai pristato pirmą intradurinės intramedulinės spinalinės teratomos atvejį Lietuvoje, kuris, nors ir nepasireiškė būdingais simpto mais ir požymiais, tačiau buvo sėkmingai diagnozuotas ir gydytas, taip pat suaugusiųjų spinalinės teratomos literatūros apžvalgą.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

Section: Patho Log I Cal Find Ingsmentioning

confidence: 99%

See 3 more Smart Citations

Adult-onset spinal teratoma: a case report and review

Blank¹,

Terbetas²,

Neverauskiene³

et al. 2019

View full text Add to dashboard Cite

show abstract

Mature teratoma of conus medullaris: A case report and review of literature

Eslami,

Ilaghi,

Shahabinejad

et al. 2023

Clinical Case Reports

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Key Clinical MessageIn conus medullaris, mature teratomas are rare. We report a case of a 40‐year‐old man who presented with urinary incontinence, low back pain, and muscle weakness. Magnetic resonance imaging revealed a mass in conus medullaris (T11–L1), further confirmed as a mature teratoma by pathological examination. We identified 63 cases of conus medullaris teratoma over the past two decades by systematically analyzing the case reports. Findings demonstrated that most cases were diagnosed in the fourth decade of life, with the majority of cases (57.6%) being male. Lower back pain, radiating pain in the extremities, hypoesthesia, and urinary dysfunction are the most common clinical presentations among patients with teratoma of conus medullaris. Mature teratoma is the dominant pathologic subtype of teratomas in this region, comprising more than 95% of cases. Our case highlights the importance of considering spinal teratoma as a differential diagnosis in patients presenting with urinary incontinence and lumbar pain.

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A comprehensive review of adult onset spinal teratomas: analysis of factors related to outcomes and recurrences

Prasad

Divya

2019

Eur Spine J

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A case of conus medullaris teratoma

Cited by 4 publications

References 5 publications

Adult-onset spinal teratoma: a case report and review

Adult-onset spinal teratoma: a case report and review

Mature teratoma of conus medullaris: A case report and review of literature

A comprehensive review of adult onset spinal teratomas: analysis of factors related to outcomes and recurrences

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