A Case of Chondrodermatitis Nodularis Chronica Helicis with an Autoantibody to Denatured Type II Collagen

Yoshinaga, Eiji; Enomoto, Utako; Fujimoto, Nozomu; Ohnishi, Yoshihiro; Tajima, S; Ishibashi, Akira

doi:10.1080/00015550152384308

Cited by 13 publications

(2 citation statements)

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“…Perforating dermatoses and transepidermal elimination: There is a general agreement that CNCH is a disorder of transepidermal elimination, in which damaged dermal connective tissue (primarily collagen) is engulfed and eliminated by a hyperplastic epidermis [ 15 , 23 ]. Other perforating dermatoses are elastosis perforans serpiginosa, perforating collagenosis, perforating folliculitis, and Kyrle’s disease [ 24 ]. In a study that examined 57 lesions from 45 patients, the absence of chondritis/perichondritis in histological examinations supports that CNCH is primarily of a dermal/epidermal origin rather than being a cartilaginous disorder, and a number of its histological features are common to several other perforating dermatoses [ 22 ].…”

Section: Reviewmentioning

confidence: 99%

Review of the Etiopathogenesis and Management Options of Chondrodermatitis Nodularis Chronica Helicis

Salah¹,

Urso²,

Khachemoune³

2018

Cureus

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Chondrodermatits nodularis chronica helicis (CNCH), first described by Max Winkler in 1915, presents as a sore nodule on the helix or antihelix of the external ear. In this paper, we review the etiopathogenesis and management options of CNCH. This condition has a multifactorial etiology; however, sustained pressure from sleeping on one side is the favored theory. Currently, there are many surgical and non-surgical methods of treating CNCH. Most practitioners recommend conservative measures first in their patients, such as pressure-relieving prostheses, prior to surgical treatment. Surgery is the gold standard of therapy with cartilage and wedge excisions yielding recurrence rates of about 10%. Carbon dioxide laser and photodynamic therapy are newer treatment modalities for CNCH, yet they have recurrence rates similar to conservative therapy. In conclusion, due to the high rates of CNCH recurrence, wedge resection is the suggested treatment for CNCH after conservative measures fail.

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Section: Reviewmentioning

confidence: 99%

Review of the Etiopathogenesis and Management Options of Chondrodermatitis Nodularis Chronica Helicis

Salah¹,

Urso²,

Khachemoune³

2018

Cureus

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“…Among possible other causes, an auto-antibody against denatured type II collagen has been demonstrated in chondrodermatitis nodularis helicis. 9 Other factors, such as anatomy, vascular deficiency and trauma, are also important in its pathogenesis.…”

Section: Discussionmentioning

confidence: 99%

Coronavirus disease 2019 pandemic related chondrodermatitis nodularis helicis: the role of masks

Cascino,

Gabriele,

Pulli

et al. 2023

J. Laryngol. Otol.

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Background Chondrodermatitis nodularis helicis is a benign, but painful inflammatory condition of the ear, characterised by a tender nodule located on the helix or antihelix. This study aimed to investigate the occurrence of chondrodermatitis nodularis helicis associated with the use of coronavirus disease 2019 masks during the pandemic. Method A retrospective single-centre study was performed from February 2020 to February 2022 in the Maxillo-Facial Unit at the University Hospital of Siena, Italy. Results During the indexed period, 11 patients were affected by chondrodermatitis nodularis helicis. All patients wore a mask for more than 8 hours a day, every day for several months. Conclusion Although there is no certain proof of the correlation between masks and chondrodermatitis nodularis helicis, an increase in the incidence of this condition was highlighted in our single-centre experience in the pandemic period. The prolonged use of coronavirus disease 2019 masks may explain this correlation.

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Chondrodermatitis Nodularis Helicis Successfully Treated With Photodynamic Therapy

Gilaberte

Frías²,

Pérez-Lórenz³

2010

Arch Dermatol

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Chondrodermatitis nodularis helicis (CDNH) is a painful inflammatory condition affecting the helix of the ear. We describe 5 patients with CDNH who were successfully treated with methyl aminolevulinate photodynamic therapy (PDT). REPORT OF CASES Five patients at our clinic, 3 women and 2 men, with a mean age of 77 years (age range, 58-88 years), were diagnosed as having CDNH. All cases presented with 1 or 2 small, painful erythematous nodules, 3 of which were centered by an ulcer, on the upper part of the helix (Figure 1). Two patients also had a painful erythematous lesion on the antihelix. Pressure-relieving devices, topical corticosteroids, and cryotherapy had been previously used with little or no improvement. In addition, in 1 case the lesion was a recurrence after surgical exci-sion 2 years previously. The mean duration of the CDNH was 11.6 months (range,6-24 months).

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A Case of Chondrodermatitis Nodularis Chronica Helicis with an Autoantibody to Denatured Type II Collagen

Cited by 13 publications

References 1 publication

Review of the Etiopathogenesis and Management Options of Chondrodermatitis Nodularis Chronica Helicis

Review of the Etiopathogenesis and Management Options of Chondrodermatitis Nodularis Chronica Helicis

Coronavirus disease 2019 pandemic related chondrodermatitis nodularis helicis: the role of masks

Chondrodermatitis Nodularis Helicis Successfully Treated With Photodynamic Therapy

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