A Case of Bullous Transient Acantholytic Dermatosis

Yoo, Jae Hak; Cho, Kwang Hyun; Youn, Jai Il

doi:10.1111/j.1346-8138.1994.tb01720.x

Cited by 12 publications

(11 citation statements)

References 10 publications

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“…Such cases should be classified into the broad spectrum of acantholytic dyskeratotic diseases of Ackerman [10,11]. Similar changes reported as persistent transient acantholytic disease [6, or atypical Darier's disease [ 12,201 andor dyskeratomatosis verruciformis [I41 also belong to the group of acantholytic dyskeratosis.…”

Section: Discussionmentioning

confidence: 92%

“…In 1970, Grover [3] coined the term transient acantholytic dermatosis (TAD) for papulo-vesicular eruption, localized preferentially on the trunk, with characteristic histological pattern of pronounced acantholysis and scarce, if any, dyskeratosis [3,4] except for Darier's type variant with pronounced dyskeratosis [4]. Later there were reported various other forms of TAD: bullous [5,6] and plaque [7] variants, and persistent acantholytic dermatosis keratosis (FAD). According to number, size and duration of the lesions, they were classified into solitary (papular, nodular), multiple peTistent (Darier's disease, linear, zosteriform) and evanescent (transient acantholytic dermatosis).…”

Section: Introductionmentioning

confidence: 99%

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Disseminated papular acantholytic dyskeratosis

Ciupinska¹,

Kalbarczyk²,

Jabłońska

1998

Acad Dermatol Venereol

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We present two cases of elderly women with clinically atypical transient disseminated papular eruption, showing suprabasal epidermal clefts with dyskeratosis and acantholysis. The clinical picture did not correspond to either Darier's disease, Hailey's disease or Grover's acantholysis. In spite of clinical similarity the cases differed in course and outcome. Overlapping dyskeratosis and acantholysis varied in different specimens. The case with transient acantholytic lesions of short duration showed much more pronounced dyskeratosis than the other in which several relapses occurred in a 4-year period. Such cases defying classification belong to the heterogeneous group of papular acantholytic dyskeratosis.

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Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Disseminated papular acantholytic dyskeratosis

Ciupinska¹,

Kalbarczyk²,

Jabłońska

1998

Acad Dermatol Venereol

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“…Antihistamines can decrease itching (2, 13). In therapy-re sistant cases, oral retinoids such as etretinate (31) and isotretinoin (26,(32)(33)(34) can be used. Vitamin A (13,35) and clindamycin (36) were successfully given in some cases of TAD.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Transient Acantholytic Dermatosis with Systemic Steroids

Erős

Kovács

Károlyi

1998

The Journal of Dermatology

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A sixty-year-old man, developed 2-5 mm sized, hyperemic, itchy papules, vesicles, erosions and crusts on hyperemic base on his chest, abdomen, back, gluteal region, and proximal sites of his upper and lower extremities. The direct and indirect immunoflurescence tests were negative. Histology revealed extensive acantholysis in the epidermis in the following forms: pemphigus vulgaris-like suprabasal acantholysis, Darier-like acantholytic dyskeratosis with corps ronds, Hailey-Hailey-like suprabasal clefts, and pemphigus foliaceus-like superficial acantholysis with spongiosis. Using systemic steroids, topical drying, and reepithelising therapy, the patient was cured. He was symptom-free the first, fourth, and thirteenth months after finishing steroid therapy. We review the literature and the new subdivision of the disease according to the histological and clinical features.

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“…Papular acantholytic dyskeratosis with oral isotretinoin acquired good results [157]. Yoo (1994) reported a case of a bullous variant of transient acantholytic dermatosis in a 59-year-old female. Each bullous lesion lasted several weeks and healed without scarring.…”

Section: Bullous Dermatosesmentioning

confidence: 99%

“…Histopathologic examination revealed an intraepidermal vesicle low in the epidermis. The lesions cleared after 2 months of isotretinoin therapy [158]. Patients with recessive dystrophic epidermolysis bullosa (RDEB) A total of 20 patients with RDEB aged 15 years or older were treated daily for 8 months with isotretinoin (with a targeted dosage of 0.5 mg/kg/d).…”

Section: Bullous Dermatosesmentioning

confidence: 99%