A Case of Breast Cancer with Cartilaginous and Osseous Metaplasia

Kato, Aya; Tani, Kazuyuki; Nakayama, Hirotaka; Shiraishi, Ryuji; Rino, Yasushi; Masuda, Munetaka

doi:10.4030/jjcs.39.865

Cited by 1 publication

(2 citation statements)

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“…Conversely, hematogenous metastases early after surgery have been frequently observed, and the commonly reported metastatic sites are the lung, brain, and bone. As in our case, ER and PgR statuses are often negative, and chemotherapy resistance occurs in many cases [ 2 ]. In a previous report, patients with tumors that had pseudosarcomatous-predominant components were associated with worse prognosis than those with epithelial-predominant components (5-year overall survival: 28% vs. 62%) [ 2 , 3 ].…”

Section: Discussionmentioning

confidence: 73%

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Acute arterial occlusive disease due to tumor thrombus from lung metastasis of breast cancer with cartilaginous and osseous metaplasia: a case report

et al. 2023

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Background Tumor embolization due to venous infiltration of breast cancer pulmonary metastases is very rare. Case presentation A 72-year-old female was diagnosed with triple-negative breast cancer. Neoadjuvant chemotherapy was discontinued because of progressive disease, and a right mastectomy with sentinel lymph node biopsy was performed. The pathological analysis of surgical specimens revealed carcinoma with cartilaginous and/or osseous metaplasia. At 22 months after surgery, lung metastasis was observed, and 6 months after initiating treatment for lung metastases, she complained of sudden numbness in the left-lower limb with trouble walking. Ultrasonography showed an embolism in the left popliteal artery, and contrast computed tomography showed enlarged lung metastases and infiltration of the left-upper lobe disease into the left superior pulmonary vein and left atrium. Acute arterial occlusive disease in the left-lower limb caused by the tumor embolism was suspected, so an endovascular thrombectomy was performed. Tumor emboli were removed by embolectomy catheter. Conclusion This report of lung metastasis from breast cancer with cartilaginous and/or osseous metaplasia and acute lower-limb artery occlusion due to a tumor thrombus adds useful information to the literature on these extremely rare cases.

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Section: Discussionmentioning

confidence: 73%

“…Breast cancer with cartilaginous and/or osseous metaplasia is classified as a special type of invasive breast cancer that occurs in 0.003–0.12% of all cases [ 1 , 2 ]. The clinical features include a larger tumor size than observed in other types of invasive ductal carcinoma and rapid growth.…”

Section: Discussionmentioning

confidence: 99%