A Case of Angiotropic Large Cell Lymphoma Primarily Discovered in Biopsy Specimens from Liver and Bone Marrow

Abstract

Objective and Importance: We describe an unusual site for angiotropic large cell lymphoma (ALCL) diagnosed from liver and bone marrow biopsy specimens. ALCL is a rare, multifocal, exclusively intravascular and generally fatal disorder of high-grade non-Hodgkin’s lymphoma. Clinical Presentation: The patient, a 70-year-old woman, presented with hepatosplenomegaly, anaemia, and disturbed liver function tests. Conclusion: As far as we know, and according to the available literature, liver and bone marrow biopsies have never been reported as being primary sites of ALCL.