A case of angiosarcoma arising on a closed shunt in a patient with chronic renal failure

Kamijo, Fuminao; Kiniwa, Yukiko; Goto, Yasufumi; Shirota, Shiho; Kobayashi, Akihiro; Tanaka, Asuka; Fukuzawa, Masao; Saida, Toshiaki

doi:10.1016/j.jaad.2010.09.727

Cited by 2 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Characteristics of 29 angiosarcoma case reports [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] including ours in HD or post-renal transplant patients are summarized in Table 2 (Italics text in Table 2 indicates items that apply to our case). There were many complaints of pain or a mass, as in our case.…”

Section: Discussionmentioning

confidence: 99%

Axillary arterial angiosarcoma in a nonfunctioning arteriovenous fistula limb of a patient undergoing hemodialysis: case report with literature review

et al. 2019

View full text Add to dashboard Cite

A 54-year-old man was admitted to our hospital with a painful left axillary mass. He had a 27-year history of hemodialysis for end-stage kidney disease because of chronic glomerulonephritis. He had a right radial artery-cephalic vein arteriovenous fistula and left nonfunctioning arteriovenous fistula. Computed tomography imaging showed a left axillary arterial mass with peripheral hematoma and multiple lung tumors. On hospital day 3, he showed disturbances in consciousness as well as enlargement of the axillary mass and hematoma. We performed emergency surgery to resect the left axillary tumor. The patient was diagnosed with angiosarcoma upon histopathological examination of the resected specimen on hospital day 15. Because his condition was extremely poor, we provided supportive care to him, not chemotherapy. He expired on hospital day 25. Angiosarcoma remains a rare disease; however, this case highlights the importance of including angiosarcoma in the differential diagnosis for upper extremity pain in patients undergoing hemodialysis.

show abstract

Section: Discussionmentioning

confidence: 99%

Axillary arterial angiosarcoma in a nonfunctioning arteriovenous fistula limb of a patient undergoing hemodialysis: case report with literature review

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Most of these breast cancer patients had undergone a Halsted radical mastectomy [ 6 ]. There are also case reports of patients who developed STS on closed shunts in renal transplant and chronic kidney disease [ 7 ]. No racial preponderance has been observed in this syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, there have been case reports of patients who developed this syndrome while taking chronic systemic immunosuppressive medications, chemotherapy, and in patients with acquired immunodeficiency syndrome. This raises the possibility that systemic, not only local immunosuppression, may have a role in the development of lymphangiosarcoma [ 6 , 7 ]. Interestingly, some authors postulate that mutations in the DNA repair genes BRCA1 and BRCA2 predispose to angiosarcomas after treatment for breast cancer [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…Not all malignant endothelial cells will be positive for this marker; thus, a panel of immunohistochemical stains should be used to avoid false-negatives. Diagnostically helpful stains include CD31, CD34, FLI-1, von Willebrand factor, and factor VIII [ 2 , 3 , 5 , 7 ]. In addition, numerous lymphatic associated antibodies have been developed, including podoplanin (D2–40), lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), prospero homeobox protein 1, and vascular endothelial growth factor receptor 3 (VEGFR-3) [ 2 , 3 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Stewart-Treves Syndrome: A Case Report and Review of the Literature

et al. 2016

View full text Add to dashboard Cite

The Stewart-Treves syndrome is a rare and deadly entity, which is defined as angiosarcoma arising in the setting of chronic lymphedema. It typically presents in women who develop lymphedema in the upper extremity secondary to axillary lymph node dissection for breast cancer surgery. It is extremely uncommon in the lower extremities as a result of idiopathic chronic lymphedema. Here, we present the case of a 63-year-old female patient with idiopathic chronic lymphedema of the lower extremities having morbid obesity (BMI 82.6) and multiple comorbidities. She developed multiple confluent, hemorrhagic and necrotic elevated purple-black papules in the lower extremities, for which the initial diagnosis was cellulitis. Because there was no improvement with antibiotics, a lower extremity ultrasound and biopsy was performed which showed multiple masses in the left inner upper calf with solid and cystic components. The pathology results of the punch biopsies were consistent with angiosarcoma. Immunohistochemical studies revealed positivity for CD31, FLI-1, and a high Ki-67 proliferation rate. Because of the patient's weight and medical comorbidities, no further extensive diagnostic tests were performed to detect metastatic disease, and because of contraindications, no further medical treatment was provided. The patient subsequently died 1 month after diagnosis.

show abstract

A case of angiosarcoma arising on a closed shunt in a patient with chronic renal failure

Cited by 2 publications

References 3 publications

Axillary arterial angiosarcoma in a nonfunctioning arteriovenous fistula limb of a patient undergoing hemodialysis: case report with literature review

Axillary arterial angiosarcoma in a nonfunctioning arteriovenous fistula limb of a patient undergoing hemodialysis: case report with literature review

Stewart-Treves Syndrome: A Case Report and Review of the Literature

Contact Info

Product

Resources

About