A case of allergic contact dermatitis caused by goalkeeper gloves

Aizawa, Atsuko; Ito, Akiko; Masui, Yukiko; Sasaki, Koichi; Ishimura, Yutaka; Numata, Masahiro; Abe, Riichiro

doi:10.1111/cod.13011

Cited by 7 publications

(4 citation statements)

References 4 publications

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“…1,3-Diphenylguanidine (DPG), 1,3-di- o -tolylguanidine (DTG), and 1,2,3-triphenylguanidine (TPG) (Table ) are synthetic chemicals used in the vulcanization of rubber and other polymers, which are employed in the production of tires, building materials, flooring, furniture, toys, leather products, foot-wear, electronic equipment, and synthetic rubber gloves. − The respective annual production of DPG and DTG in the United States in 2015 was 454–9070 and 94 tons () and that in Europe in 2018 was 1000–10000 and 100–1000 tons. , DPG, DTG, and TPG can be leached from rubber products into the environment, resulting in potential human exposure.…”

Section: Introductionmentioning

confidence: 99%

Occurrence of 1,3-Diphenylguanidine, 1,3-Di-o-tolylguanidine, and 1,2,3-Triphenylguanidine in Indoor Dust from 11 Countries: Implications for Human Exposure

2023

Environ. Sci. Technol.

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1,3-Diphenylguanidine (DPG), 1,3-di-o-tolylguanidine (DTG), and 1,2,3-triphenylguanidine (TPG) are synthetic chemicals widely used in rubber and other polymers. Nevertheless, limited information is available on their occurrence in indoor dust. We measured these chemicals in 332 dust samples collected from 11 countries. DPG, DTG, and TPG were found in 100%, 62%, and 76% of the house dust samples, at median concentrations of 140, 2.3, and 0.9 ng/g, respectively. The sum concentrations of DPG and its analogues varied among the countries in the following decreasing order: Japan (median: 1300 ng/g) > Greece (940) > South Korea (560) > Saudi Arabia (440) > the United States (250) > Kuwait (160) > Romania (140) > Vietnam (120) > Colombia (100) > Pakistan (33) > India (26). DPG accounted for ≥87% of the sum concentrations of the three compounds in all countries. DPG, DTG, and TPG exhibited significant correlations (r: 0.35−0.73; p < 0.001). Elevated concentrations of DPG were found in dust from certain microenvironments (e.g., offices and cars). Human exposure to DPG through dust ingestion were in the ranges 0.07−4.40, 0.09− 5.20, 0.03−1.70, 0.02−1.04, and 0.01−0.87 ng/kg body weight (BW)/day for infants, toddlers, children, teenagers, and adults, respectively.

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Section: Introductionmentioning

confidence: 99%

Occurrence of 1,3-Diphenylguanidine, 1,3-Di-o-tolylguanidine, and 1,2,3-Triphenylguanidine in Indoor Dust from 11 Countries: Implications for Human Exposure

2023

Environ. Sci. Technol.

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“…p-tert-Butylphenol-Formaldehydharz liegt in verschiedenen Varianten vor; eine relevante davon ist das in der (europäischen) Standardreihe enthaltene Harz. In Japan wurden bei einem 16-jährigen Torwart mit chronischem Handekzem in fünf Paar Torwarthandschuhen, die er benutzte, verschiedene Phenolverbindungen nachgewiesen, die mit dem oben genannten routinemäßig getesteten Harz kreuzreagierten [173]. Ein 44-jähriger finnischer Arbeiter in der Lebensmittelverpackungsindustrie entwickelte eine Kontaktdermatitis an den Handgelenken, während er zwei Maschinen bediente, mit denen Getränkedosen von innen sprühbeschichtet wurden; bei diesem Patienten wurde eine ACD gegen das dafür verwendete Phenolformaldehydharz diagnostiziert [174].…”

Section: Ergebnisseunclassified

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Uter¹,

Werfel

Lepoittevin

et al. 2021

Kompass Dermatol

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Kontaktallergie (Sensibilisierung) und daraus resultierende allergische Kontaktdermatitis (ACD) sind von erheblicher Tragweite aus Sicht des Gesundheitswesens. Für die vorliegende Übersichtsarbeit hierzu wurden alle passenden Artikel aus dem Zeitraum 2018–2019 per systematischer Suche in Medline und Web of Science<sup>TM</sup> ermittelt; außerdem wurden alle verfügbaren Ausgaben der Fachzeitschriften „Contact Dermatitis“ und „Dermatitis“ manuell durchsucht und so eine frühere, ähnliche Übersichtsarbeit fortgeschrieben und neu fokussiert. Neue Allergene ebenso wie bekannte Allergene, die in neuem Expositionskontext gefunden wurden oder deren Bedeutung in sonstiger Hinsicht neu bewertet wurde, werden in Abschnitten nach Substanzklasse gegliedert beschrieben (z. B. Metalle, Konservierungsmittel, Duftstoffe). Als gemeinsames Ergebnis zahlreicher Untersuchungen fällt sowohl ein Mangel an Informationen über die Produktzusammensetzung auf, z. B. in Bezug auf ein neu beschriebenes Allergen in Leinenturnschuhen (Dimethylthiocarbamylbenzothiazolsulfid), als auch vor allem die mangelnde Kooperativität von Herstellern von Blutzuckermessgeräten bzw. Insulinpumpen. Zu den letztgenannten Geräten hat eine internationale Zusammenarbeit zwischen Dermatologen und Chemikern gezeigt, dass sie bei zahlreichen Diabetikern schwere ACD verursachen, indem sie Isobornylacrylat bzw. N,N’-Dimethylacrylamid freisetzen. Eine verbesserte und vollständige Deklaration der Inhaltsstoffe für Produkte alle Art – und nicht nur, wie wir es derzeit in Europa haben, bei Kosmetika (abgesehen von der vollständigen Auflistung der Duftstoffe) – muss auf die legislative Agenda gesetzt werden.

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“…p-tert-Butylphenol formaldehyde resin exists in a number of varieties; the resin included in the (European) baseline series is one of these and is of importance. In the case of a 16-year-old Japanese goalkeeper with chronic hand eczema, different phenol compounds were detected-which did cross-react with above-mentioned routinely tested resin-in five pairs of goalkeeper's gloves used by the patient [173]. A Finnish 44-year-old food packaging industry worker developed contact dermatitis of the wrists when operating two machines spray-coating the interior of beverage cans; the patient was diagnosed as having ACD to the phenol formaldehyde resin used for that purpose [174].…”

Section: Plastic Monomers and Rubbermentioning

confidence: 99%

Contact Allergy—Emerging Allergens and Public Health Impact

Uter

Werfel

Lepoittevin

et al. 2020

IJERPH

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Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact Dermatitis” and “Dermatitis” were manually searched, covering the years 2018–2019, thereby extending and re-focusing a previous similar review. New allergens, or previously described allergens found in a new exposure context or of other current importance, are described in sections according to substance classes, e.g., metals, preservatives, fragrances. As a common finding in many investigations, a lack of information on product composition has been noted, for instance, regarding a newly described allergen in canvas shoes (dimethylthiocarbamylbenzothiazole sulfide) and, most notably, absence of co-operation from manufacturers of glucose-monitoring devices and insulin pumps, respectively. These latter devices have been shown to cause severe ACD in a considerable number of diabetic patients caused by the liberation of isobornyl acrylate and N,N’-dimethylacrylamide, respectively, as demonstrated by an international collaboration between dermatologists and chemists. Improved and complete ingredient labelling for all types of products, and not just as we have with cosmetics at present (apart from full listing of fragrance substances) in Europe, must be put on the legislative agenda.

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A case of allergic contact dermatitis caused by goalkeeper gloves

Cited by 7 publications

References 4 publications

Occurrence of 1,3-Diphenylguanidine, 1,3-Di-o-tolylguanidine, and 1,2,3-Triphenylguanidine in Indoor Dust from 11 Countries: Implications for Human Exposure

Occurrence of 1,3-Diphenylguanidine, 1,3-Di-o-tolylguanidine, and 1,2,3-Triphenylguanidine in Indoor Dust from 11 Countries: Implications for Human Exposure

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Contact Allergy—Emerging Allergens and Public Health Impact

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