A Case of Aggressive Recurrent Intracranial Subdural Hematoma Associated with Angiosarcoma Originating from the Skull

Kanazawa, Tokunori; Miwa, Takaki; Akiyama, Takahiro; Ohara, Kentaro; Kosugi, Kenzo; Nishimoto, Masaaki; Yoshida, Kazunari

doi:10.1016/j.wneu.2019.02.168

Cited by 2 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Angiosarcoma arises in the head and neck, breast, lung, liver, heart, bone, or spleen and tends to metastasize to other parts of the body. [11][12][13] Metastatic angiosarcoma has a hematogenous mechanism, 14 with many cases of brain metastasis reported. 12 However, there have been few reports of cases of primary CNS angiosarcoma.…”

Section: Discussionmentioning

confidence: 99%

Multifocal primary central nervous system angiosarcoma: illustrative case

Hirai¹,

Tao²,

Nishimura

et al. 2023

Journal of Neurosurgery: Case Lessons

View full text Add to dashboard Cite

BACKGROUND Angiosarcoma is a malignant mesenchymal tumor derived from vascular endothelial cells in which a primary intracranial origin is extremely rare. Most previous reports of primary central nervous system (CNS) angiosarcoma have been solitary cases. OBSERVATIONS The authors report a case of primary CNS angiosarcoma that caused the development of multiple disseminated cerebral hemorrhagic lesions within a short period of time. This rapid progression of symptoms resulted in the death of the patient. During surgery, several nodules suggestive of a tumor were removed from just below the surface of the brain, mixed into the hematoma. A pathological examination revealed atypical cells mimicking blood vessels in the subarachnoid space that were positive for specific vascular endothelial markers. LESSONS In this case, multifocal angiosarcoma occurred on the brain surface and ventricles, suggesting cerebrospinal fluid dissemination. If multiple cerebral hemorrhages are found on the brain surface, multifocal angiosarcoma should also be considered.

show abstract