A Case of Acute ST-Segment Elevation Myocardial Infarction as an Initial Presentation of Essential Thrombocythemia in a Young Healthy Male

Abstract

In this report, we present the case of a 34-year-old young male from the Middle East who was admitted to the emergency department with ST-elevation myocardial infarction (STEMI) as the first manifestation without known cardiovascular risk factors (CVRFs). On examination, he showed signs of tachypnea and bilateral basal inspiratory crackles. The patient was treated with a loading dose of aspirin, clopidogrel, and anticoagulants, and underwent emergency coronary angiography, which revealed thrombotic occlusion of the proximal left anterior descending artery (LAD). His laboratory investigations revealed increased platelet count, and genetic studies showed a positive JAK2 V617F gene mutation. Upon discharge, he was regularly followed up and remained stable without any further thrombotic or hemorrhagic complications.