A case-control study of obesity as a risk factor for carpal tunnel syndrome in a population of 600 patients presenting for independent medical examination

Stallings, Shawn P.; Kasdan, Morton L.; Soergel, Trevor M.; Corwin, Hal M.

doi:10.1016/s0363-5023(97)80153-0

Cited by 94 publications

(57 citation statements)

References 11 publications

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“…However, altered sensory thresholds have been shown in nondiabetic obese individuals, which suggests that obesity alone may increase one's risk for peripheral neuropathic disorders [60]. For example, obesity has been found to be a risk factor for carpal tunnel syndrome [61]. However, whether obesity is an independent risk factor for development of neuropathic pain disorders is not entirely clear.…”

Section: Mechanisms: Explaining the Relationship Between Pain And Ovementioning

confidence: 99%

Overview of the relationship between pain and obesity: What do we know? Where do we go next?

Janke¹,

Collins²,

Kozak³

2007

JRRD

183

141

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Abstract-Overweight/obesity and pain are significant problems of increasing prevalence; understanding the relationship between the two is the focus of a growing body of research. Findings from this review support a likely relationship between increasing weight and pain conditions such as osteoarthritis and low back pain. Longitudinal studies suggest overweight/obesity early in life is a risk factor for pain, and the co-occurrence of pain and overweight/obesity negatively affects quality of life. The mechanism of relationship is unknown but is hypothesized to include mechanical and metabolic abnormalities, possibly secondary to lifestyle choices. Observations from a few studies demonstrate that treatments for obesity reduce pain secondary to weight loss. Few studies examine both pain and weight as primary outcomes, and variability in measurement makes comparisons and conclusions difficult. Research should focus on expanding knowledge about mechanisms of the relationship between pain and obesity, testing explanatory models addressing their co-occurrence, and developing treatments that most effectively target this comorbidity.

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Section: Mechanisms: Explaining the Relationship Between Pain And Ovementioning

confidence: 99%

Overview of the relationship between pain and obesity: What do we know? Where do we go next?

Janke¹,

Collins²,

Kozak³

2007

JRRD

183

141

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show abstract

“…In a number of case-control studies, obesity was strongly associated with CTS and was independent of diabetes mellitus as a risk factor. [11][12][13] The literature associating obesity and LBP is limited. In a longitudinal study of weight and magnetic resonance imaging findings in the lumbar spine, persistent weight 425 kg/m 2 was associated with an increased risk of degenerative discs, but no clinical correlations were made.…”

Section: Introductionmentioning

confidence: 99%

Musculoskeletal findings in obese subjects before and after weight loss following bariatric surgery

et al. 2006

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Objective: To determine the point prevalence of painful musculoskeletal (MSK) conditions in obese subjects before and after weight loss following bariatric surgery. Design: Longitudinal, interventional, unblended. Subjects: Forty-eight obese subjects (47 women, one man, mean age 4479 years; mean body mass index (BMI) 5178 kg/m 2 ) recruited from an academic medical center bariatric surgery program. Measurements: Comorbid medical conditions; MSK findings; BMI; Western Ontario McMaster Osteoarthritis Index (WOMAC) for pain, stiffness and function; and SF-36 s for quality of life. Methods: Consecutive subjects were recruited from the University Hospitals of Cleveland Bariatric Surgery Program. Musculoskeletal signs and symptoms and non-MSK comorbid conditions were documented at baseline and at follow-up. Subjects completed the SF-36 s and the WOMAC questionnaires. Analyses were carried out for each MSK site, fibromyalgia syndrome (FMS) and for the cumulative effect on the spine, upper and lower extremities. The impact of change in comorbid medical conditions, BMI, physical and mental health domains of the SF-36 s on the WOMAC pain subscale score was evaluated. SF-36 s outcomes were compared to normal published controls. Results: Forty-eight subjects were available for baseline and a follow-up assessment 6-12 months after gastric bypass surgery. They lost an average of 41715 kg and the mean BMI decreased from 5178 to 3677 kg/m 2 . Baseline comorbid medical conditions were present in 96% before surgery and 23% after weight loss. There was an increased prevalence of painful MSK conditions at baseline compared to general population frequencies. Musculoskeletal complaints had been present in 100% of obese subjects before, and 23% after weight loss. The greatest improvements occurred in the cervical and lumbar spine, the foot and in FMS (decreased by 90, 83, 83 and 92%, respectively). Seventy-nine percent had upper extremity MSK conditions before and 40% after weight loss. Before surgery, 100% had lower extremity MSK conditions and only 37% did after weight loss. The WOMAC subscale and composite scores all improved significantly, as did the SF-36 s . Change in BMI was the main factor impacting the WOMAC pain score. Conclusion: There was a higher frequency of multiple MSK complaints, including non-weight-bearing sites compared to historical controls, before surgery, which decreased significantly at most sites following weight loss and physical activity. These benefits may improve further, as weight loss may continue for up to 24 months. The benefits seen with weight loss indicate that prevention and treatment of obesity can improve MSK health and function.

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“…Kadın/erkek oranı 1,8/1 ile 10/1 arasında değişkenlik gösterdiği çalışmalar bildirilmiştir (1,17). Bizim çalışmamızda hastaların 1190 (%80,6)'ı kadın, 286 (%19,4)'sı erkekti.…”

Section: Bulgularunclassified

Demographic and electrophysiological characteristics of patients with prediagnosis of carpal tunnel syndrome admitted to electromyography laboratory

Eren¹,

Büyükgöl²,

İlik³

et al. 2017

Eur J Ther

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ÖZAmaç: Karpal tünel sendromu (KTS) üst ekstremitenin en sık görülen tuzak nöropatisidir. Yaş, cinsiyet, obezite, mesleki faktörler önemli risk faktörleridir. Tanıda elektrofizyolojik çalışmalar önemlidir. Bu ça-lışmada, elektrofizyoloji laboratuarımıza KTS ön tanısı ile başvuran hastaların demografik özelliklerini ve klinik ön tanı ile elektromyografi (ENMG) tanısının uygunluğu değerlendirmeyi amaçladık.Yöntemler: Çalışma, elektrofizyoloji laboratuarına haziran 2014-temmuz 2015 tarihleri arasında KTS ön tanısı ile yönlendirilen 2913 hastanın geriye dönük olarak taranması ile yapıldı. Sonuç: Karpal tünel sendromunun kadınlarda daha fazla görüldüğü-nü, yaş ve ellerin aşırı kullanımın olduğu meslek gruplarının KTS gelişimi için önemli risk faktörleri olduğu desteklemektedir. Hastaların %49,3'ünde normal elektrofizyolojik bulguların saptanması gereksiz ENMG istemlerinin yapıldığını düşündürmektedir. Anahtar Kelimeler: Karpal tünel sendromu, demografik özellikler, etyoloji, ön tanı ABSTRACTObjective: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper limbs. Age, sex, obesity, and occupational factors are important risk factors. Electrophysiological studies are important for diagnosis. In this study, we aimed to evaluate the demographic characteristics of patients with a prediagnosis of CTS admitted to our electrophysiology laboratory and investigate the correlation between the clinical prediagnosis and electromyography diagnosis. Methods:The study comprised 2913 patients with a prediagnosis of CTS admitted to our electrophysiology laboratory between June 2014 and July 2015.Results: In this study, 2913 patients (2286 women and 627 men) were evaluated. In total, 1476 patients (50.7%) were detected to have CTS. Of which, 1190 (80.6%) were female and 286 (19.4%) were male; 357 (24.2%) patients were aged <40 years and 1119 (75.8%) were aged >40 years. Furthermore, 461 patients (32%) were farmers who engaged in agriculture and livestock farming. Conclusion:CTS is more common in women; age and professional groups with overuse of hands are important risk factors for the development of CTS. Detection of normal electrophysiological findings in 49.3% of patients suggests that unnecessary ENMG requests are made.

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A case-control study of obesity as a risk factor for carpal tunnel syndrome in a population of 600 patients presenting for independent medical examination

Cited by 94 publications

References 11 publications

Overview of the relationship between pain and obesity: What do we know? Where do we go next?

Overview of the relationship between pain and obesity: What do we know? Where do we go next?

Musculoskeletal findings in obese subjects before and after weight loss following bariatric surgery

Demographic and electrophysiological characteristics of patients with prediagnosis of carpal tunnel syndrome admitted to electromyography laboratory

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