A case-control study of cataract in Oxfordshire: some risk factors.

Abstract

SUMMARY Three hundred patients with cataract and 609 control subjects with the same age-sex distribution were interviewed in a study of cataract in Oxfordshire, England. The risks associated with severe diarrhoea, glaucoma, and work on a military base have been demonstrated. Population attributable risks were calculated for those and other risk factors.Cataract is the major cause of blindness worldwide and yet it is frequently stated that most cataracts are of unknown aetiology. In the Western world it usually occurs late in life and has therefore been called senile cataract. In some third world countries it is more prevalent than in the West and develops at an earlier age. Our suggestion that diarrhoea might be an important factor in these countries' has been supported by the results of a careful study from India.2 Several risk factors for cataract, including diabetes, glaucoma, and high levels of plasma glucose and urea, were identified in a study in Edinburgh,3 but they did not include diarrhoea. We have conducted a similar study in Oxfordshire with particular interest in diarrhoea, medical and drug history, smoking, drinking, and place of work. It

Pharmacological actions and potential uses of Momordica charantia: a review

“…Diabetes mellitus has been consistently identified in many studies as the most important risk factor for cataract in Western countries (Hiller et al, 1983;Van-Heyningen and Harding, 1988;Harding et al, 1989). Although surgery is effective, strategies aimed to prevent or delay development of cataract remains the preferred approach to confront the global problem.…”

Cataract May Affect the Axial Length of High Myopes in Adults

“…The relationship between myopia and age-related cataracts is not clear, despite several clinic-based [1][2][3][4][5][6][7][8] and population-based investigations [9,10]. The aetiology, pathogenesis, and treatment of myopia have been hotly debated in the ophthalmic community for decades.…”

Evaluation of Ex Vivo Anticataract Activity of Ethanolic Extract of Alstonia Scholaris Leaves on Dexamethasone-Induced Cataract by Using Isolated Goat Lens

“…Combined factors of heritage, ultraviolet light exposure, diet, some metabolic disorders, quality of life, cationic pump malfunction, and lens metabolism disorder are believed to have a role in cataract formation. The increased incidence of cataracts in diabetic patients is also well known [4]. Presently, surgery is the only approach for the treatment of cataract, and while favorable outcomes are quite predictable, the limited number of surgeons is underdeveloped countries, and the high cost of surgery have made cataract a major health problem.…”