A Cannabinoid Fuel Cell Capable of Producing Current by Oxidizing Δ⁹-Tetrahydrocannabinol

Abstract

We report the development of a current-producing H-Cell that relies on the oxidation of Δ 9 -tetrahydrocannabinol (THC), which is the primary psychoactive ingredient in marijuana. We found through systematic investigation of several variables that power densities could be improved 5-fold. Moreover, a real-time signal in a rudimentary THC sensor was observed at varying concentrations of THC. Given the growing societal interest in the detection of THC, our studies lay the foundation for the development of a marijuana breathalyzer.

Electrochemical Oxidation of Δ9-Tetrahydrocannabinol at Nanomolar Concentrations

“…The method is dependent on the selective electrochemical oxidation of Δ 9 -THC (1) to p-THCQ (2) (Figure 2) and was recently translated to establish the first cannabinoid fuel cell technology. 23 Nonetheless, a number of questions remain regarding the applicability of this electrochemical-based strategy to real-world applications. For example, our initial experiments required a 6.6 mM concentration of Δ 9 -THC (1), which is significantly higher than what would be observed on breath samples.…”

“…Inspired by the history of the alcohol breathalyzer, we originally sought to identify a fundamental THC oxidation that could operate electrolytically, with the ultimate goal being to develop a fuel cell driven by THC similar to the state-of-the-art alcohol fuel cells found in modern breathalyzers. The method is dependent on the selective electrochemical oxidation of Δ 9 -THC ( 1 ) to p -THCQ ( 2 ) (Figure ) and was recently translated to establish the first cannabinoid fuel cell technology . Nonetheless, a number of questions remain regarding the applicability of this electrochemical-based strategy to real-world applications.…”