A butyrolactone lignan disaccharide from Flacourtia ramontchi

Chemistry and application of 4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde

“…MeCOCH 2 CO 2 Et with 1 under reflux in ethanol containing liquor ammonia gives exclusively the pyranopyridine 103 (X = OH, R = OEt) identical with that obtained by treating 1 with 160 (R = OEt) indicating that the formation of 160 (R = OEt) from MeCOCH 2 CO 2 Et and ammonia predominates over the base catalysed condensation of the acetoacetic ester with the aldehyde 1; the enamine 160 (R = OEt) thus formed reacts with 1 giving 103 (X = OH, R = OEt) [108]. Similar condensation of MeCOCH 2 CO 2 Me with 1 in refluxing methanol-ammonia gives the fused pyridine 103 (X = OH, R = OMe) [108] in contrast to the previously reported exclusive formation of 104 (R = Chr, R 1 = Me, X = Y = CO 2 Me) [145].…”

Protective effects of Flacourtia indica aerial parts extracts against paracetamol-induced hepatotoxiciy in rats

“…Previous phytochemical investigation on this plant resulted in the isolatation of β-sitosterol (a well-known phytosterol), β-sitosterol-β-Dglucopyranoside, ramontoside, butyrolactone lignan disaccharide [3], and flacourtin [4]. In our previous study, we also reported the presence of coumarin such as scoparone and aesculetin [2].…”

In Vitro Antioxidant Activity of Aqueous Ethanol Extract of Flacourtia Indica Merr.

“…Significant progress has been made over the past years towards a much more comprehensive understanding of some of the important pharmacological components of Flacourtia indica. Isolatation of β-sitosterol (a well-known phytosterol), β-sitosterol-β-Dglucopyranoside, ramontoside, butyrolactone lignan disaccharide, flacourtin, coumarin such as scoparone and aesculetin has been described [11][12][13] . Fruits contain protein and sucrose; barks yield tannin and flacoutin, aphenolic glucoside ester 10 .…”