A Brief Review of Self-Healing Polyurethane Based on Dynamic Chemistry

Lee, Won-Ji; Oh, Hyeon-Gyeong; Cha, Sang‐Ho

doi:10.1007/s13233-021-9088-2

Cited by 47 publications

(24 citation statements)

References 105 publications

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“…Self-healing carriers, i.e., carriers that restore structural properties after deformation and failure, are gaining attention from the research community since there is a constant need to extend the lifespan, improving the safety and performance of materials, especially in biomedical applications [ 73 ]. The self-healing behavior is due to the dynamic re-build of the relatively weak bonds such as hydrogen bonds, ionic interactions, etc.…”

Section: Resultsmentioning

confidence: 99%

Development of Polyurethane/Peptide-Based Carriers with Self-Healing Properties

Grădinaru¹,

Bercea²,

Lupu³

et al. 2023

Polymers

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In situ-forming gels with self-assembling and self-healing properties are materials of high interest for various biomedical applications, especially for drug delivery systems and tissue regeneration. The main goal of this research was the development of an innovative gel carrier based on dynamic inter- and intramolecular interactions between amphiphilic polyurethane and peptide structures. The polyurethane architecture was adapted to achieve the desired amphiphilicity for self-assembly into an aqueous solution and to facilitate an array of connections with peptides through physical interactions, such as hydrophobic interactions, dipole-dipole, electrostatic, π–π stacking, or hydrogen bonds. The mechanism of the gelation process and the macromolecular conformation in water were evaluated with DLS, ATR-FTIR, and rheological measurements at room and body temperatures. The DLS measurements revealed a bimodal distribution of small (~30–40 nm) and large (~300–400 nm) hydrodynamic diameters of micelles/aggregates at 25 °C for all samples. The increase in the peptide content led to a monomodal distribution of the peaks at 37 °C (~25 nm for the sample with the highest content of peptide). The sol–gel transition occurs very quickly for all samples (within 20–30 s), but the equilibrium state of the gel structure is reached after 1 h in absence of peptide and required more time as the content of peptide increases. Moreover, this system presented self-healing properties, as was revealed by rheological measurements. In the presence of peptide, the structure recovery after each cycle of deformation is a time-dependent process, the recovery is complete after about 300 s. Thus, the addition of the peptide enhanced the polymer chain entanglement through intermolecular interactions, leading to the preparation of a well-defined gel carrier. Undoubtedly, this type of polyurethane/peptide-based carrier, displaying a sol–gel transition at a biologically relevant temperature and enhanced viscoelastic properties, is of great interest in the development of medical devices for minimally invasive procedures or precision medicine.

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Section: Resultsmentioning

confidence: 99%

Development of Polyurethane/Peptide-Based Carriers with Self-Healing Properties

Grădinaru¹,

Bercea²,

Lupu³

et al. 2023

Polymers

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“…The previous review articles have reviewed the self-healing surfaces, materials, and principles, 11,28,29 bioinspired self-healing materials, 30 bioinspired superwettability surfaces, and their applications. 2,5,31−33 Some of them focus on the self-healing superhydrophobic/superoleophobic materials, which follow the mechanism of migrating low surface energy chemicals from the storage layer to the damaged surface or regenerating the surface topology.…”

Section: Introductionmentioning

confidence: 99%

Self-Healing Superwetting Surfaces, Their Fabrications, and Properties

et al. 2022

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The research on superwetting surfaces with a self-healing function against various damages has progressed rapidly in the recent decade. They are expected to be an effective approach to increasing the durability and application robustness of superwetting materials. Various methods and material systems have been developed to prepare selfhealing superwetting surfaces, some of which mimic natural superwetting surfaces. However, they still face challenges, such as being workable only for specific damages, external stimulation to trigger the healing process, and poor self-healing ability in the water, marine, or biological systems. There is a lack of fundamental understanding as well. This article comprehensively reviews self-healing superwetting surfaces, including their fabrication strategies, essential rules for materials design, and self-healing properties. Self-healing triggered by different external stimuli is summarized. The potential applications of self-healing superwetting surfaces are highlighted. This article consists of four main sections: (1) the functional surfaces with various superwetting properties, (2) natural self-healing superwetting surfaces (i.e., plants, insects, and creatures) and their healing mechanism, (3) recent research development in various self-healing superwetting surfaces, their preparation, wetting properties in the air or liquid media, and healing mechanism, and (4) the prospects including existing challenges, our views and potential solutions to the challenges, and future research directions.

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“…Dynamic covalent crosslinked networks can be produced by crosslinking pre-polymers and small molecules (e.g., chain extender) via dynamic covalent bonds. These materials need external stimuli (often heat) to be healable [ 1 , 2 , 3 , 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Bio-Based Healable 2K PU Textile Coating for Durable Applications

Smet

Vanneste

2022

Polymers

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A biobased healable 2K polyurethane (PU) coating incorporating a Schiff base was synthesized and applied as a thin coating on textiles. The Schiff base, made out of cystine and vanillin, contained reversible imine and disulfide bonds and was used as a chain extender in PU synthesis. The FT-IR analysis indicated the successful incorporation of the Schiff base in the PU backbone. Compared with control PU coatings, the healable bio-based PU coating with the Schiff base showed very good healing properties using heat as external stimuli: a healing recovery of 75% was obtained after applying a 2 N scratch and complete recovery of the resistance to hydrostatic pressure. SEM analysis revealed complete closure of the scratch after healing for 30 min at 90 °C. The healing properties are attributed to the synergy of the dual-dynamic metatheses of the imine and disulfide bonds.

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A Brief Review of Self-Healing Polyurethane Based on Dynamic Chemistry

Cited by 47 publications

References 105 publications

Development of Polyurethane/Peptide-Based Carriers with Self-Healing Properties

Development of Polyurethane/Peptide-Based Carriers with Self-Healing Properties

Self-Healing Superwetting Surfaces, Their Fabrications, and Properties

Bio-Based Healable 2K PU Textile Coating for Durable Applications

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