A Brief Discussion of Mechanism of Butylphthalide in Treatment of Ischemic Cerebrovascular Disease and its Potential Clinical Applicationin Treatment of Multiple Sclerosis

Abstract

A Chinese traditional medicine Butylphthalide (NBP) has been proved effects in ischemic cerebrovascular disease. Here we discuss the mechanism of NBP in treatment of ischemic stroke, and find its capability in penetrating and modulating Blood-brain barrier (BBB), reducing harmful inflammation and formation of scars in injury CNS tissue, which implicate the potential application of NBP in treatment of Multiple Sclerosis (MS).