A Boy With Sjogren’s Syndrome and Recurrent Parotitis Who Presented With Suspicious of Allergic and Immunological Disease: Review of the Literature

Abstract

Recurrent parotitis (RP) is an acute, severe inflammation of one or both parotid glands which are major salivary glands in younger children. Most common causes of RP include bacterial and viral infections, juvenile RP, anatomic abnormalities and auto-immune diseases. Association of RP with allergic and immunological diseases has been rarely reported. Primary Sjogren's syndrome (pSS) is a rare auto-immune disease, particularly in childhood. Rarely, pSS may be diagnosed in men, although it predominantly affects women. Here, we reported a 4-year-old boy who presented with suspicion of allergic diseases, recurrent swelling of salivary glands, positive anti-nuclear and anti-Ro/SS-B antibodies, positive rheumatoid factor and mild hypergammaglobulinemia but not apparent sicca symptoms.