A biosensor based on Fe3O4@MXene-Au nanocomposites with high peroxidase-like activity for colorimetric and smartphone-based detection of glucose

Fei, Jianwen; Yang, Wei; Dai, Yin; Xu, Wei; Fan, Huizhu; Zheng, Yani; Zhang, Jun; Zhu, Wanying; Hong, Junli; Zhou, Xuemin

doi:10.1007/s00604-023-05900-1

Cited by 7 publications

(1 citation statement)

References 42 publications

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“…The point-of-care testing has become popular to meet the needs of on-site detection, which possesses excellent portability and operability . Although test strips were widely used for semiquantitative detections, their practical application has been limited because of their poor stability and low sensitivity .…”

Section: Introductionmentioning

confidence: 99%

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

Dai,

Wen,

Fan

et al. 2024

ACS Appl. Nano Mater.

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Hydrogen peroxide (H 2 O 2 ) and glutathione (GSH) have been reported to be associated with a variety of diseases. Therefore, the accurate and rapid determination of H 2 O 2 and GSH was very important. The traditional assay was the colorimetric method, which suffered from the bottleneck of single-mode analysis. In this work, we designed a dual-mode fluorescence and colorimetric sensor for detecting H 2 O 2 and GSH based on bifunctional Fe, Co-CDs, which possessed peroxidase (POD)mimetic activity and fluorescence property. Concretely, the Fe, Co-CDs catalyzed oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to a blue product (oxTMB) with the help of H 2 O 2 , which could be inhibited by GSH. Meanwhile, the fluorescence of Fe, Co-CDs weakened with increasing oxTMB, realizing the fluorescence analysis of H 2 O 2 and GSH. In fluorescence and colorimetric sensors, the detection limit (LOD) of H 2 O 2 could reach as low as 0.54 μM and 0.81 μM, as well as the LOD of GSH was 0.39 and 0.61 μM, respectively. Besides, the smartphone-assisted hydrogel sensor was developed for on-site detection of GSH via color change. This study not only designed a dual-mode sensor for dual-target detection but also provided insights for further exploration of multifunctional nanozymes.

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Section: Introductionmentioning

confidence: 99%

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

Dai,

Wen,

Fan

et al. 2024

ACS Appl. Nano Mater.

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Smartphone-enhanced nanozyme sensors: Colorimetric and fluorescence sensing techniques

Sahare,

Singh,

Sahoo

et al. 2024

Biosensors and Bioelectronics: X

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Recent advancements in nanozyme hydrogel based system for enhanced sensing applications

Makkar,

Sarawagi,

Priyadarshi

et al. 2024

Biosensors and Bioelectronics: X

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A biosensor based on Fe3O4@MXene-Au nanocomposites with high peroxidase-like activity for colorimetric and smartphone-based detection of glucose

Cited by 7 publications

References 42 publications

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

Smartphone-enhanced nanozyme sensors: Colorimetric and fluorescence sensing techniques

Recent advancements in nanozyme hydrogel based system for enhanced sensing applications

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A biosensor based on Fe3O4@MXene-Au nanocomposites with high peroxidase-like activity for colorimetric and smartphone-based detection of glucose

Cited by 7 publications

References 42 publications

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H2O2 and Glutathione

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H2O2 and Glutathione

Smartphone-enhanced nanozyme sensors: Colorimetric and fluorescence sensing techniques

Recent advancements in nanozyme hydrogel based system for enhanced sensing applications

Contact Info

Product

Resources

About

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione