“…Optimal design of experiments for inverse problems governed by ordinary differential equations or differential-algebraic equations appear in numerous works; examples include [11,13,17,28,67]. Recent works also include OED for inverse problems constrained by PDEs; see e.g., [4,25,42,55,57,82,105,108]. Bayesian approaches to OED for nonlinear inverse problems governed by computationally challenging models were presented in [58,59]; these articles use polynomial chaos expansions and Monte Carlo to estimate the OED objective, and use a stochastic optimization approach to compute the optimal design.…”