A biflavonoid glycoside fromLomatogonium carinthiacum(Wulf) Reichb

Abstract

A biflavonoid glycoside with a new carbon skeleton, named carinoside A, was isolated from the n-BuOH crude extract of the whole plant of Lomatogonium carinthiacum (Wulf) Reichb. The structure of the new compound was elucidated by using spectroscopic methods, including UV, IR, HR-ESI-MS and extensive 1D and 2D NMR techniques.

The isolation and structural elucidation of three new biflavonoid glycosides fromLomatogonium carinthiacum

“…The A and B rings were called as the partial structure I and the A 0 and B 0 rings as the partial structure II. It is similar to those of carinoside A (Wang et al 2015), except for the sugar moieties. The 13 C NMR spectrum of 1 (Table S1) also showed the presence .3 belong to two Larabinofuranoses, which was confirmed by comparing their spectral data with those reported in the literature (Gorin & Mazurek 1975).…”

“…The molecular formula was determined to be C 44 H 42 O 21 by HR-ESI-MS at m/z 907.2295 [M þ H] þ . 1 H and 13 C NMR spectra (Table S3) of compound 3 were similar to those of carinoside A (Wang et al 2015), except for B ring of the flavone aglycone. Namely, the A 2 B 2 system in carinoside A was substituted by the ABX system in compound 3 and this was confirmed by the carbon signals at d c 121.7, 114.0, 150.4, 146.3, 116.5 and 119.5, and 121.8, 113.8, 150.2, 146.2, 116.5 and 119.5.…”

“…Terpenoids and flavonoids (Massia et al 1981;Jia and Yuan 2011) have been reported from L. carinthiacum. In our previous studies, flavonoids (Bao et al 2014), two new monoterpene glucoside derivatives (Wang, Dai, et al 2014), two new xanthones (Wang, Bao, et al 2014), and a biflavonoid glycoside (Wang et al 2015) were isolated from the CHCl 3 , EtOAc and n-BuOH crude extract of this plant. In the continuation of our work on the constituents of the n-BuOH crude extract from L. carinthiacum, three biflavonoid glycosides were isolated.…”