A better understanding of the term radial scar

King, Tari A.; Scharfenberg, John C.; Smetherman, Dana H.; Farkas, Emily A.; Bolton, John S.; Fuhrman, George M.

doi:10.1016/s0002-9610(00)00506-7

Cited by 43 publications

(34 citation statements)

References 15 publications

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“…For example, mammographically detected RS are usually larger and seem to have a higher incidence of associated carcinoma than RS discovered incidentally [11,18,20]. In this regard, the lack of underestimation of carcinoma in the series of Philpotts et al [26] could reflect the fact that 50% (4/8) of RS in their series were incidental findings after SCNB of calcifications, while in the present series only 7% (3/43) of RS were incidentally found after SCNB of calcifications.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical significance of RS is threefold: first, both at mammography [6,[8][9][10][11] and histopathologic examination [1,2,[12][13][14][15][16] it is difficult to differentiate these lesions from carcinoma. Second, discrete foci of carcinoma may be found within or adjacent to some RS [9][10][11][17][18][19][20]. Third, recent data suggests that RS may be an independent risk factor for breast cancer [21].…”

Section: Introductionmentioning

confidence: 99%

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Radial scars diagnosed at stereotactic core-needle biopsy: surgical biopsy findings

et al. 2006

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We retrospectively reviewed surgical biopsy findings of lesions diagnosed as radial scars (RS) at stereotactic core-needle biopsy (SCNB). RS was diagnosed in 52 of 1415 (3.7%) consecutive mammographically detected lesions that underwent 14-gauge automated SCNB. Subsequent surgical biopsy findings were available for 43 lesions in 41 women constituting the study group. Of these 43 lesions, histopathological analysis of the surgical specimen yielded RS in 27 (63%), RS plus atypical ductal hyperplasia (ADH) in 8 (18%), RS plus carcinoma in five (12%), and only carcinoma in three (7%). Carcinomas underestimated at SCNB (n=8) were two in situ carcinomas, two invasive ductal carcinomas not otherwise specified, and four tubular carcinomas. A statistically significant difference (P=0.02) was found between the mean pathologic size of RS without carcinoma and of RS containing carcinoma. Mammographic features could not be used reliably to predict the presence of carcinoma at excision of lesions diagnosed as RS at SCNB. The results suggest that the diagnosis of RS at 14-gauge SCNB of mammographically detected lesions is an indication for surgical biopsy because of the high prevalence of carcinoma in these lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Radial scars diagnosed at stereotactic core-needle biopsy: surgical biopsy findings

et al. 2006

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“…Radial sclerosing lesions (RSLs) have been recognized for almost a century and variously described under different names such as radial scars, sclerosing lesions, scleroelastotic lesions, indurative mastopathies, nonencapsulated sclerosing lesions, sclerosing papillary proliferations, and, if larger than 1.0 cm, complex sclerosing lesions [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Management of radial sclerosing lesions of the breast diagnosed using percutaneous vacuum-assisted core needle biopsy: recommendations for excision based on seven years’ of experience at a single institution

Resetkova

Edelweiss

Albarracin

et al. 2008

Breast Cancer Res Treat

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Architectural distortion on imaging, residual abnormality on post-biopsy mammogram and the presence of proliferative changes and/or epithelial atypia on SCNB were parameters leading to increased performance of surgical excision in our series. No diagnoses were upgraded to malignancy after excision of RSLs, suggesting that more extensive sampling by a 9- or 11-gauge SCNB device, followed by meticulous correlation of radiological and pathological findings and close clinical/radiological follow-up, could obviate surgical excision in the majority of RSL cases without associated atypia on SCNB.

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“…Although a few studies (1,3,(13)(14)(15)(16)(17)(18)(19)(20)(21) have investigated some of these histologic diagnoses, the degree of risk association has not been as well established, and there is need to confirm the significance of these diagnoses when made by community pathologists.…”

Section: Introductionmentioning

confidence: 99%