A Benefit–Risk Conceptual Framework for Biologic Use During Pregnancy: A Mini‐Review
Laura M. Bozzi,
Melanie H. Jacobson,
Emily Yost
et al.
Abstract:Recent reports related to in utero exposure of marketed immunosuppressive biologics led to clinical recommendations to delay live vaccinations for infants due to the concern of reduced vaccine effectiveness and/or increased risk of vaccine‐related disease. These delays can increase the risk of children contracting vaccine preventable diseases, yet the alternative cessation of biologics during pregnancy may result in increased autoimmune disease activity for the pregnant person, raising complex benefit–risk (B‐… Show more
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