China plays an important role in the international trade of agricultural commodities. Considering the dynamic reactive nitrogen (Nr) losses of agricultural systems in China, a hypothesis was proposed that crop conversion in China would be correlated with the extent of crop trade, influencing Nr losses in agricultural systems. The objective of this study was to verify the hypothesis based on a hybrid approach, which incorporated life cycle analysis (LCA), copula-Markov Chain Monte Carlo (MCMC) simulation, and copula sampling. The approach was proven to be of benefit in (a) evaluating Nr losses in crop planting based on a LCA framework, (b) identifying dependencies and co-movements of the correlated variables in planting structures and crop trade using copula-MCMC simulations, and (c) recognizing fluctuations in Nr losses of crop planting in the future using copula-based sampling method. The planting structures and international trade of four types of crops (i.e., wheat, soybeans, maize, and rice) in twenty provinces of China indicated significant correlations, thus supporting the initial hypothesis. With the improvement of self-sufficiency in crop production, especially soybeans, Nr losses from the crop production of China in 2025 and 2030 would decrease by 8.43% and 4.26%, compared with those in 2018 (i.e., 1916.74 kt N).