A Aggressive Osteosarcoma of Mandible with Lung Metastasis in a 5 Year Child: A Case Report

Abstract

Abstract:Osteosarcoma is a malignant mesenchymal tumor whose cancerous cells produce osteoid matrix. It is the most common primary malignant bone tumor, accounting for approximately 20% of the sarcomas, but osteosarcoma of mandible is rare only 5% of the osteosarcomas occur in the jaws and occur mainly in adult population in their later part of the life. They present various clinical and histological aspects, as well as variable disease progression and outcome. Mandibular osteosarcoma are slow growing tumors and have better prognosis compared to other site. Lung is the most common site of metastasis in osteosarcoma mainly in the long bones, in craniofascial osteosarcoma lung metastasis is a rare findings. We are presenting a case of osteosarcoma of mandible in 5 year child with aggressive initial presentation. Keywords: Aggressive Mandibular Osteosarcoma, Lung MetastasisOsteosarcoma(OS) is the most common primary malignant bone neoplasm, predominantly occurring in long bones and occasionally in the maxillofacial area. Accounts 5-9% of OS, Maxilla and the mandible are the most involved site.1-4 Mandibular osteosarcoma is often considered a distinct entity because of its predilection to older patients (mean age: 34 to 36 years). In addition, metastases are rare and the prognosis is significantly better and rarely develops distant metastases, when compared to its counterpart in long bones.3-8 we are presenting a case of 5 year old male child a case of osteosarcoma of mandible with lung metastasis.