A 75-year-old woman with multifocal jejunal strictures

Lee, Hui Yann; Howarth, Gina; Willert, Robert P.

doi:10.1136/gutjnl-2014-307895

Cited by 31 publications

(3 citation statements)

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“…The ulceration of EATLs usually appears large and deep, with sharp edges, along with strictures in the majority of patients of this type (4/6, 66.7%), which could be seen in some previous case reports. [ 13 15 16 ] However, this finding is different from those of a previous case series, which found that the small intestine exhibited multiple circular or semicircular shallow ulcerations. [ 10 ] A correct real-time endoscopic impression is important to make an early diagnosis of EATL.…”

Section: Discussioncontrasting

confidence: 92%

“…Endoscopy can identify abnormal mucosa in most patients; however, it is nonspecific. To date, only a few case reports[ 7 8 9 10 11 12 13 14 15 16 ] have detailed the endoscopic features of EATLs. The endoscopic appearances of EATL are still largely unknown.…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 2 6 ] To date, only a few case reports have detailed the endoscopic morphologic features of EATLs. [ 7 8 9 10 11 12 13 14 15 16 ] In addition, due to a lack of specific endoscopic features, it is difficult to distinguish EATLs and other GI diseases, such as inflammatory bowel disease (IBD) and GI solid tumors, at the time of presentation. To advance knowledge of this disease, we retrospectively reviewed the cases of EATLs diagnosed within a 13-year period in a single tertiary center and summarized the clinical characteristics and endoscopic features of the EATLs.…”

Section: Introductionmentioning

confidence: 99%

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Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Chen

Zhang

Shi

2022

Saudi J Gastroenterol

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Background: Enteropathy-associated T-cell lymphoma (EATL) is a rare but aggressive primary gastrointestinal lymphoma. The initial complaints of EATL patients are usually gastrointestinal symptoms, but the diagnosis is very difficult. Endoscopy can identify abnormal mucosa in most patients. However, the endoscopic appearance of EATL is still largely unknown. Methods: In this retrospective study, we investigated the endoscopic and clinical features of patients with EATLs at a tertiary center, from January 2008 to October 2020. Results: From a total of 248 patients with primary intestinal lymphoma, only 11 patients were finally diagnosed with EATLs, all of which were EATL type II. Men were affected twice as commonly as women. The median patient age was 47 years. The most common initial symptom was diarrhea (63.6%). Five patients (45.4%) were at late stage (IV) at diagnosis. The endoscopic appearances were classified into four distinct types: ulcerative type (54.5%), epithelial mass type (18.2%), diffuse infiltration type (9.1%), and nodular type (18.2%). The small bowel was the most common site of involvement (72.7%). The initial endoscopic impression of lymphoma was made in only 3 patients (27.3%). Only 4 patients (36.4%) were histologically confirmed as having EATLs based on the initial biopsy specimen. Five patients (45.5%) received emergency surgery. The median overall survival (OS) was 8 months. The use of chemotherapy and the absence of emergency surgery were associated with a significantly better median OS ( P < 0.05). Conclusions: EATL may show various endoscopic appearances, and its prognosis is poor. Endoscopists should obtain more knowledge of EATL in order to make an early diagnosis.

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Section: Discussioncontrasting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Chen

Zhang

Shi

2022

Saudi J Gastroenterol

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Non-Neoplastic Pathology of the Gastrointestinal Tract

2020

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This book concisely summarises non-neoplastic gastrointestinal (GI) pathology and provides histopathologists aiming to refresh or expand their knowledge with a practical approach to the interpretation of biopsies. It focuses on GI biopsies, but also covers the pathology of resections and other organs where appropriate. The editor and contributors bring their expertise as practicing diagnostic pathologists across Europe and the US. Examples of topics include inflammatory bowel disease, infections, vascular disorders, and inflammatory conditions specific to various anatomical sites. Fact sheets, practice points and tables facilitate rapid assimilation of information and enhance the reader's experience, and with additional access to the full online version, including expandable images on Cambridge Core, achieve accuracy every time. High-quality illustrations are also numerous, and references are relevant and reliable. This book is a practical, readable and up-to-date asset for any pathologist encountering GI biopsies.

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Preface

2020

Non-Neoplastic Pathology of the Gastrointestinal Tract

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A 75-year-old woman with multifocal jejunal strictures

Cited by 31 publications

References 2 publications

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Endoscopic features and clinical outcomes of enteropathy-associated T-cell lymphoma: A tertiary center retrospective study

Non-Neoplastic Pathology of the Gastrointestinal Tract

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