A 60-Year-Old Indian Male With Altered Sensorium and Extensive Lymphoma of the Scalp

Yadav, Budhi Singh; Bansal, Anshuma; Sharma, Suresh C.; Malhotra, Pankaj; Ghosh, Nilanjan; Holdhoff, Matthias; Shustov, Andrei R.; Chamberlain, Marc C.; Newton, Herbert B.; Kumethkar, Priya; Raizer, Jeffrey; Glass, Jon; Morris, Gloria J.

doi:10.1053/j.seminoncol.2013.04.014

Cited by 4 publications

(12 citation statements)

References 57 publications

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“…The diagnostic criteria for PLB include that the tumor mass is isolated from the bone, and there is no lesions in other parts of the body, or no spread systemic lesions for at least 6 months. [6,13,14] The tumor found in our case met these diagnostic criteria of PLB. According to most previous literature, PCVL more often occurs in elderly populations.…”

Section: Discussionsupporting

confidence: 64%

“…When the mass gradually invades the cranial skull, dura mater, or infiltrates the cortex, corresponding focal neurologic signs appear such as headache, limb numbness, hemiplegia, and convulsions. [3,6,16,17] In our case, the patient had a history of head trauma and his scalp mass gradually increased to a large size. According to the literature, the differential diagnoses of PCVL include meningioma, metastatic infiltration, histiocytosis, subdural hematoma, plasma cell tumors, and osteomyelitis.…”

Section: Discussionmentioning

confidence: 86%

“…Diffuse positive anti-CD20 staining supports the diagnosis of diffuse large B-cell lymphoma, negative anti-CD30 staining suggests a low possibility of Hodgkin's lymphoma, and positive anti-CD3 staining often supports the diagnosis of B cell lymphoma. [6]…”

Section: Discussionmentioning

confidence: 99%

“…[6,13,16] Radiotherapy is an effective means of treating PCVL because it is a radiosensitive tumor. [6] It has been reported that the combined use of surgical treatment and radiotherapy can achieve good results [19,20] ; for most cases, surgical treatment was the initial treatment. [21] A separate systemic chemotherapy can also achieve good therapeutic effect.…”

Section: Discussionmentioning

confidence: 99%

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Head trauma complicated with primary cranial vault lymphoma

Huang

Tang

et al. 2019

Medicine

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Rationale: Primary cranial vault lymphoma (PCVL) is an extremely rare extranodal lymphoma in the skull. This case study investigates the clinical features, so as to improve the understanding of the diagnosis and therapy. Patient concerns: A 31-year-old male presented painful scalp mass at the site of 1-month-old head trauma. Diagnosis: The final diagnosis was plasma cell lymphoma, which is a rare subtype of diffuse large B-cell lymphoma based on biopsy and immunohistochemistry findings. Interventions: The patient received total tumor resection in combination with chemotherapy Outcomes: The patient survived without signs of systemic dissemination for 12 months after surgery at the time of last follow-up. Lessons: Trauma may be one of the factors that induce PCVL. The final diagnosis of PCVL depends on pathology and immunohistochemistry findings. A combined treatment of surgery, chemotherapy, and radiotherapy can achieve favorable outcomes.

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Section: Discussionsupporting

confidence: 64%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Head trauma complicated with primary cranial vault lymphoma

Huang

Tang

et al. 2019

Medicine

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“…[ 5 ] Among all cutaneous sites, the scalp is a rare site of representation. [ 6 , 7 ] The conventional therapeutics include surgery, chemotherapy, and radiotherapy. In elder patients, however, the available options were limited due to the deteriorative physical condition.…”

Section: Introductionmentioning

confidence: 99%

A 92-year-old man with primary cutaneous diffuse large B-cell non-Hodgkin's lymphoma manifesting as a giant scalp mass

Liao

Yang²,

Liu³

et al. 2017

Medicine

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Rationale:Primary cutaneous non-Hodgkin's lymphoma (NHL) is an uncommon entity, representing 10% of all extranodal NHLs. Among all cutaneous sites, the scalp is a rare site of representation.Patient concerns:A 92-year-old Chinese man visited our hospital with a multiple-nodular huge scalp mass on the right parieto-occipital regions. The mass was of 7-month duration and progressively enlarging in size.Diagnoses:On the basis of the result of biopsy, diffuse large B-cell NHL was diagnosed.Interventions:The mass was partially resected by surgery and no further treatment was conducted due to the advanced age and poor physical status.Outcomes:The tumor relapsed in situ after 6 months and the patient died after 2 years.Lessons:This case highlighted the limited access to standard treatment options in patients with advanced age. A thorough examination is necessary to decide upon the treatment for the primary cutaneous lymphoma.

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