A 6-Year Experience with Immediate Reconstruction after Mastectomy for Cancer

Noone, R. Barrett; Murphy, James B.; Spear, Scott L.; Little, John W.

doi:10.1097/00006534-198508000-00012

Cited by 121 publications

(35 citation statements)

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“…There were more delayed complications and more surgical revisions in the group RI (27,3%, RR RI vs. others = 6,4 [2,[6][7][8][9][10][11][12][13][14][15]6]; p=0,0005). Considering all complications, TRAM and RI reconstructions required more surgical revisions than LD reconstructions (RR TRAM vs. LD = 2,7 [1,[4][5]3] and RR RI vs. LD = 4,2 [2,[0][1][2][3][4][5][6][7][8]6]; p=0,0006). Twelve reconstruction failures were noted with 1 complete TRAM flap loss and 11 implants removal (6 in LDI and 5 in RI).…”

Section: Resultsmentioning

confidence: 93%

“…The mean follow-up was 8 years (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). Five patients were lost to follow-up.…”

Section: Resultsmentioning

confidence: 99%

“…1 Oncological safety of IBR has been confirmed when performing mastectomies for in situ ductal carcinoma (DCIS) and early-stage invasive breast cancers. 2,3 However, the management of operable locally advanced breast cancer (LABC) (stage IIb and III) is challenging and includes a multimodal approach with systemic therapy, radiotherapy (RT) and surgery. The ability to safely integrate postmastectomy RT into the reconstructive algorithm has become more complex and controversial.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Mastectomy with immediate breast reconstruction after neoadjuvant chemotherapy and radiation therapy. A new option for patients with operable invasive breast cancer. Results of a 20 years single institution study

Monrigal

Dauplat

Gimbergues

et al. 2011

European Journal of Surgical Oncology (EJSO)

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PurposeTo evaluate the feasability of immediate breast reconstruction (IBR) following mastectomy after neoadjuvant chemotherapy (NACT) and radiation therapy (RT) for operable invasive breast cancer (OIBC), in terms of incidence of local complications, locoregional control and survival. Patients and methodsFrom 1990 to 2008, 210 patients were treated by NACT, RT and mastectomy with IBR for OIBC. One hundred and seven patients underwent a latissimus dorsi flap with implant (LDI), 56 patients a transverse rectus abdominis musculocutaneous (TRAM) flap, 25 an autologous latissimus dorsi flap (ALD) and 22, a retropectoral implant (RI) reconstruction. ResultsForty-six (21,9%) early events were recorded: 20 necrosis, 9 surgical site infections and 6 haematomas, requiring further surgery in 23 patients. More necrosis were observed with TRAM flap reconstructions (p=0,000004), requiring more surgical revision than LD reconstructions. Seromas represented 42% of early complications in LD reconstructions. Fifty-five patients presented with late complications (26,2%) with mainly implant complications (capsular contracture, infection, dislocation, deflation) (23,6%), requiring reintervention in 14 cases. There were more delayed surgical revisions in RI reconstructions (p=0,0005). The 5 years overall and disease-free survival rates were respectively 86,7% and 75,6%. Sixty-four patients presented at least one recurrence (30,5%) with 5 local , 9 locoregional and 54 distant relapses. ConclusionThis therapeutic sequence does not seem to increase the IBR morbidity nor alter disease-free and overall survival.

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Section: Resultsmentioning

confidence: 93%

“…The mean follow-up was 8 years (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). Five patients were lost to follow-up.…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mastectomy with immediate breast reconstruction after neoadjuvant chemotherapy and radiation therapy. A new option for patients with operable invasive breast cancer. Results of a 20 years single institution study

Monrigal

Dauplat

Gimbergues

et al. 2011

European Journal of Surgical Oncology (EJSO)

View full text Add to dashboard Cite

show abstract

“…9,10 This approach ameliorates the woman's experience of breast loss and the psychological and physical problems that this causes. Immediate breast reconstruction is appropriate for most women with stage I and stage II breast cancer.…”

mentioning

confidence: 99%

Breast reconstruction following mastectomy

Bostwick

1995

CA: A Cancer Journal for Clinicians

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“…The rationale for this belief was that the added surgical trauma and risk were unwarranted in the breast cancer patient and might induce recurrence of the disease. During the 1980s investigators started performing immediate reconstruction using breast implants, without any increase in complication or local recurrence rates (134). The safety of this tactic has been repeatedly demonstrated during the past two decades (135± 137).…”

Section: Breast Reconstruction Following Mastectomy: An Alternati×e Tmentioning

confidence: 99%

Breast Cancer Surgery - Historical Evolution, Current Status and Future Perspectives

Sakorafas

2001

Acta Oncologica

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A 6-Year Experience with Immediate Reconstruction after Mastectomy for Cancer

Cited by 121 publications

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Mastectomy with immediate breast reconstruction after neoadjuvant chemotherapy and radiation therapy. A new option for patients with operable invasive breast cancer. Results of a 20 years single institution study

Mastectomy with immediate breast reconstruction after neoadjuvant chemotherapy and radiation therapy. A new option for patients with operable invasive breast cancer. Results of a 20 years single institution study

Breast reconstruction following mastectomy

Breast Cancer Surgery - Historical Evolution, Current Status and Future Perspectives

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