A 55-year-old man with hypogammaglobulinemia, lymphopenia, and unrelenting cutaneous warts

Primary Intestinal Lymphangiectasia: Four Case Reports and a Review of the Literature

“…It has been reported that two cases were successfully treated with octreotide and the endoscopic appearance of duodenum had turned nearly normal [17,80]. However, there were also cases with no such improvement after octreotide therapy [48]. MacLean et al [58] described a patient with IL who did not improve after diet intervention and octreotide acetate therapy, but who did have a good clinical response to antiplasmin therapy.…”

Clinical outcome of nutrition-oriented intervention for primary intestinal lymphangiectasia

“…For instance, octreotide was successfully used in some cases, [13,14] but there were also cases with no improvement after octreotide therapy. [15] The effect of octreotide on intestinal lymphangiectasia remains to be elucidated.…”

Generalized verrucosis: A review of the associated diseases, evaluation, and treatments

“…[35][36][37][38] The first case discussed a 19-year-old man with CVID and a 13-year history of warts that initially started on his feet as plantar warts, but subsequently spread as common or filiform warts on his hands, face, neck, and chest. Of note, the patient had low levels of circulating T cells.…”

“…38 A third case presented a 55-year-old man with hypogammaglobulinemia, unrelenting palmoplantar warts, and lymphopenia. 37 The most recent case described an 18-year-old man with multiple warts on his arms and hands, and a recent diagnosis of CVID, who again had hypogammaglobulinemia and a low CD4 1 T-cell count. 35 In all reported cases of CVID or hypogammaglobulinemia with extensive wart infection, the patients had low immunoglobulins and decreased T-cell counts.…”